• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Increasing effect of an oral intake of L-hydroxyproline on the soluble collagen content of skin and collagen fragments in rat serum.

作者信息

Aoki Mami, Suto Kouzou, Komatsu Miho, Kamimura Ayako, Morishita Koji, Yamasaki Motoo, Takao Toshifumi

机构信息

Healthcare Products Development Center, KYOWA HAKKO BIO CO., LTD., Ibaraki, Japan.

出版信息

Biosci Biotechnol Biochem. 2012;76(6):1242-4. doi: 10.1271/bbb.120058.

DOI:10.1271/bbb.120058
PMID:22790956
Abstract

We examined the effects of oral L-hydroxyproline (Hyp) on collagen in the body. After 2 weeks' administration of Hyp (0.5 or 1 g/kg) to F344 male rats, the soluble collagen content of the skin had increased, and the serum concentration of collagen peptides was correlated with the skin content of soluble collagen. This result suggests that oral Hyp augmented collagen metabolism.

摘要

相似文献

1
Increasing effect of an oral intake of L-hydroxyproline on the soluble collagen content of skin and collagen fragments in rat serum.
Biosci Biotechnol Biochem. 2012;76(6):1242-4. doi: 10.1271/bbb.120058.
2
Chemically-modified tetracycline normalizes collagen metabolism in diabetic rats: a dose-response study.化学修饰四环素使糖尿病大鼠的胶原代谢正常化：一项剂量反应研究。
J Periodontal Res. 1993 Nov;28(6 Pt 1):420-8.
3
Effect of sodium fluoride and magnesium chloride on different hydroxyproline fractions in rat liver.氟化钠和氯化镁对大鼠肝脏中不同羟脯氨酸组分的影响。
Indian J Biochem Biophys. 2012 Apr;49(2):130-3.
4
Effects of a long-term dietary xylitol supplementation on collagen content and fluorescence of the skin in aged rats.
Gerontology. 2005 May-Jun;51(3):166-9. doi: 10.1159/000083988.
5
Effects of dimethoate on collagen metabolism in rats.
Indian J Med Res. 1991 Dec;94:452-6.
6
The changes in various hydroxyproline fractions in aortic tissue of rabbits are closely related to the progression of atherosclerosis.主动脉组织中各种羟脯氨酸馏分的变化与动脉粥样硬化的进展密切相关。
Lipids Health Dis. 2010 Mar 9;9:26. doi: 10.1186/1476-511X-9-26.
7
Hydroxyproline-containing dipeptides and tripeptides quantified at high concentration in human blood after oral administration of gelatin hydrolysate.口服明胶水解物后，人血液中高浓度定量的含羟脯氨酸二肽和三肽。
Int J Food Sci Nutr. 2010 Feb;61(1):52-60. doi: 10.3109/09637480903257711.
8
Effect of protein malnutrition on the metabolism of dermal collagen in the rat.蛋白质营养不良对大鼠皮肤胶原蛋白代谢的影响。
Ital J Biochem. 1980 Jan-Feb;29(1):1-12.
9
Effect of chronic exposure to nitrogen dioxide on collagen fractions content in skin of guinea pigs.长期接触二氧化氮对豚鼠皮肤中胶原蛋白组分含量的影响。
Acta Biol Med Ger. 1976;35(7):1023-5.
10
Effect of Prolyl-hydroxyproline (Pro-Hyp), a food-derived collagen peptide in human blood, on growth of fibroblasts from mouse skin.食物来源的胶原蛋白肽脯氨酰羟脯氨酸（Pro-Hyp）对人血液中鼠皮肤成纤维细胞生长的影响。
J Agric Food Chem. 2009 Jan 28;57(2):444-9. doi: 10.1021/jf802785h.

引用本文的文献

1
Role of Nutritional Elements in Skin Homeostasis: A Review.营养元素在皮肤稳态中的作用：综述
Biomolecules. 2025 Jun 3;15(6):808. doi: 10.3390/biom15060808.
2
Pulsed electrical stimulation and amino acid derivatives promote collagen gene expression in human dermal fibroblasts.脉冲电刺激和氨基酸衍生物可促进人真皮成纤维细胞中胶原蛋白基因的表达。
Cytotechnology. 2024 Feb;76(1):139-151. doi: 10.1007/s10616-023-00604-z. Epub 2023 Nov 9.
3
Improvement of dermal parameters in aged skin after oral use of a nutrient supplement.口服一种营养补充剂后老年皮肤的皮肤参数改善。
Clin Cosmet Investig Dermatol. 2018 Apr 30;11:195-201. doi: 10.2147/CCID.S150269. eCollection 2018.