Department of Neurological Sciences, Medical School of São José do Rio Preto, São José do Rio Preto, SP, Brazil.
Neurosurg Rev. 2013 Jan;36(1):117-22; discussion 122. doi: 10.1007/s10143-012-0407-0. Epub 2012 Jul 13.
The purpose of this study was to correlate the morphology of giant intracranial aneurysms (GIA) with their clinical presentation. Eighty patients with GIA, 14 males and 66 females, were studied. Univariate and multivariate analyses were made to test the associations between morphological and clinical features. The main locations of the unruptured GIA included the carotid cavernous segment, and for the ruptured GIA, the most frequent were the carotid supraclinoid and middle cerebral arteries. There was a significant association among communicating arteries (CA) of "bad" quality and presence of thrombus and calcification (TC). The risk of rupture is 8 times higher in patients with CA of "bad" quality and 11 times higher in patients without TC. GIA are more frequent in the cavernous segment. There is a high rupture risk in the middle cerebral artery. CA of "bad" quality are associated with TC. The rupture risk is significantly higher in patients without TC.
本研究旨在探讨巨大颅内动脉瘤（GIA）的形态与临床表现之间的关系。研究纳入 80 例 GIA 患者，其中男性 14 例，女性 66 例。采用单因素和多因素分析方法检验形态学和临床特征之间的关联。未破裂 GIA 的主要部位包括颈内动脉海绵窦段，而破裂 GIA 最常见的部位是颈内动脉虹吸段和大脑中动脉。交通动脉（CA）质量差与血栓和钙化（TC）之间存在显著关联。CA 质量差的患者破裂风险增加 8 倍，无 TC 的患者破裂风险增加 11 倍。GIA 更常见于海绵窦段。大脑中动脉破裂风险较高。CA 质量差与 TC 相关。无 TC 的患者破裂风险显著升高。
