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脑型弓形虫病合并播散性结核病

Cerebral toxoplasmosis combined with disseminated tuberculosis.

作者信息

Hwang Eui Ho, Ahn Poong Gi, Lee Dong Min, Kim Hyeok Su

机构信息

Department of Neurosurgery, Dae-Ah Hando General Hospital, Ansan, Korea.

出版信息

J Korean Neurosurg Soc. 2012 May;51(5):316-9. doi: 10.3340/jkns.2012.51.5.316. Epub 2012 May 31.

Abstract

A 24-year-old man presented with mental change, fever, abdominal pain, tenderness and palpable mass on the lower abdomen. He was a non-Korean engineer and did not accompany a legal guardian, so medical history taking was difficult due to his mental status. Brain magnetic resonance imaging showed multiple rim-enhanced lesions of the brain, and abdominal computed tomography showed huge paraspinal abscess. Chest X-ray and computed tomography showed poorly defined nodular opacities. We initially thought that this patient was infected with toxoplasmosis with typical cerebral image finding and immunoglobulin laboratory finding of cerebrospinal fluid and serum study. The abdominal abscess was confirmed as tuberculosis through the pathologic finding of caseous necrosis. We used anti-tuberculosis medication and anti-toxoplasmosis medication for almost 4 months, and then his clinical state and radiological findings were considerably improved.

摘要

一名24岁男性出现精神状态改变、发热、腹痛、压痛及下腹部可触及肿块。他是一名非韩国籍工程师,且没有法定监护人陪同,因其精神状态,病史采集困难。脑部磁共振成像显示脑部有多个环状强化病灶,腹部计算机断层扫描显示巨大的椎旁脓肿。胸部X线和计算机断层扫描显示边界不清的结节状阴影。我们最初认为该患者感染了弓形虫病,有典型的脑部影像学表现以及脑脊液和血清学检查的免疫球蛋白实验室检查结果。通过干酪样坏死的病理检查结果,腹部脓肿被确诊为结核病。我们使用抗结核药物和抗弓形虫药物治疗了近4个月,之后他的临床状态和影像学表现有了显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb9/3393871/5e726174d861/jkns-51-316-g001.jpg

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