Maksimova M Iu, Domashenko M A, Ionova V G, Mikhal'chenko V N, Syskina E N, Okhtova F R
Zh Nevrol Psikhiatr Im S S Korsakova. 2011;111(12 Pt 2):22-7.
Haemostatic parameters: platelet aggregation, hematocrit, fibrinogen, antithrombin III, fibrinolytic activity and euglobulin lysis time, plasminogen, plasminogen activator and anti-activator activity, thrombin- antithrombin and plasmin-antiplasmin complexes and serum von Willebrand factor were studied at the most acute stage of cardioembolic stroke (1-7 days after development of neurological symptoms). State of the vascular wall was assessed using the "cuff"-test. The activation of hemostasis in patients with cardioembolic stroke was characterized by the hypercoagulation and decrease of fibrinolysis and athrombogenic potential of vessel wall properties (antiaggregation, fibrinolytic and anticoagulative). In conclusion, haemostatic disbalance and decreasing of athrombotic potential of the vessel wall may be the indicator of embolism in patients with cardioembolic stroke.
研究了心脏栓塞性中风最急性期（神经症状出现后1 - 7天）的血小板聚集、血细胞比容、纤维蛋白原、抗凝血酶III、纤溶活性和优球蛋白溶解时间、纤溶酶原、纤溶酶原激活物和抗激活物活性、凝血酶 - 抗凝血酶和纤溶酶 - 抗纤溶酶复合物以及血清血管性血友病因子。使用“袖带”试验评估血管壁状态。心脏栓塞性中风患者止血的激活表现为高凝状态、纤溶和血管壁特性的抗血栓形成潜力（抗聚集、纤溶和抗凝）降低。总之，止血失衡和血管壁抗血栓形成潜力降低可能是心脏栓塞性中风患者栓塞的指标。
