Su Y X
Department of Pathology, Shanghai Second Medical University.
Zhonghua Bing Li Xue Za Zhi. 1990 Sep;19(3):218-20.
Vimentin is an important cytoskeleton protein for the biological function of macrophages. Alterations of vimentin filaments of CP-activated macrophages stained with FITC-labeled anti-vimentin antibody were observed under immunofluorescence microscope. Activated macrophages showed changes with the following characteristics: the intensity of immunofluorescence of vimentin was increased; the filaments of vimentin became thicker than those of normal macrophages when they were treated with colchicine; and the arrangement of vimentin filaments was parallel in direction to the polarization of the activated macrophages.
波形蛋白是巨噬细胞生物学功能的一种重要细胞骨架蛋白。在免疫荧光显微镜下观察了用异硫氰酸荧光素（FITC）标记的抗波形蛋白抗体染色的CP激活巨噬细胞的波形蛋白丝的变化。激活的巨噬细胞呈现出以下特征性变化：波形蛋白的免疫荧光强度增加；用秋水仙碱处理后，波形蛋白丝比正常巨噬细胞的更粗；并且波形蛋白丝的排列方向与激活的巨噬细胞的极化方向平行。
