慢性阻塞性肺疾病的综合治疗方法。

An integrated approach to the medical treatment of chronic obstructive pulmonary disease.

机构信息

Asthma and COPD Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

出版信息

Med Clin North Am. 2012 Jul;96(4):811-26. doi: 10.1016/j.mcna.2012.05.002.

DOI:10.1016/j.mcna.2012.05.002

Abstract

COPD is a treatable condition for which careful and objective evaluation of patients’ lung function, symptoms, exercise capacity, and exacerbation history on an ongoing basis is essential so that treatments may be individualized as much as possible. Although the comparative effectiveness of drug classes has not yet been tested completely in COPD, virtually all inhaled COPD therapies improve lung function, quality of life, and reduce COPD exacerbations, which fulfills the major goals of care. Pulmonary rehabilitation is safe, effective, and a crucial component of COPD therapy. Newer therapies have been developed with the specific purpose of reducing COPD exacerbations and should be prescribed to individuals who have evidence of recurrent exacerbations despite maximal inhaled maintenance medications.

摘要

COPD 是一种可治疗的疾病，需要持续仔细和客观地评估患者的肺功能、症状、运动能力和加重病史，以便尽可能对治疗进行个体化。虽然药物类别的比较效果尚未在 COPD 中完全测试，但几乎所有吸入性 COPD 治疗都能改善肺功能、生活质量并减少 COPD 加重，这满足了护理的主要目标。肺康复是安全有效的，是 COPD 治疗的重要组成部分。新的治疗方法是为减少 COPD 加重而专门开发的，应该开给那些尽管使用了最大吸入维持药物但仍有反复加重证据的患者。