Institut fuer Pharmazeutische Biologie, Rheinische Friedrich Wilhelms-Universität, Bonn, Germany.
Phytochemistry. 2013 Jul;91:158-64. doi: 10.1016/j.phytochem.2012.06.016. Epub 2012 Jul 14.
Maytansinoid compounds are ansa antibiotics occurring in the bacterium Actinosynnema pretiosum, in mosses and in higher plants such as Putterlickia verrucosa (E. Meyer ex Sonder) Szyszyl. The disjunct occurrence of maytansinoids has led to the consideration that plant-associated bacteria may be responsible for the presence of maytansinoids in P. verrucosa plants. Investigation of the bacterial community of this plant by molecular methods led to the observation that A. pretiosum, a maytansine-producing bacterium, is likely to be an inhabitant of the rhizosphere and the endorhiza of P. verrucosa.
美登素类化合物是一种ansa 抗生素，存在于放线菌 Actinosynnema pretiosum 中，苔藓和高等植物如 Putterlickia verrucosa（E. Meyer ex Sonder）Szyszyl 中。美登素类化合物的不连续出现导致人们认为与植物相关的细菌可能是 P. verrucosa 植物中存在美登素类化合物的原因。通过分子方法对该植物的细菌群落进行调查，观察到产生美登素的放线菌 A. pretiosum 可能是 P. verrucosa 的根际和内生菌的栖息者。
