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成人膀胱外翻的处理:5 例报告。

Management of bladder exstrophy in adulthood: report of 5 cases.

机构信息

Pediatric Division, Urology Department, Cairo University, Abu El Rish Hospital, Cairo, Egypt.

出版信息

J Pediatr Urol. 2013 Oct;9(5):575-8. doi: 10.1016/j.jpurol.2012.06.004. Epub 2012 Jul 15.

DOI:10.1016/j.jpurol.2012.06.004
PMID:22796269
Abstract

OBJECTIVE

To report our experience in the management of adult classic bladder exstrophy.

PATIENTS AND METHODS

During 1977-2006 we treated five adult males presenting with classic exstrophy-epispadias complex. Patient age at presentation ranged from 17 to 30 with a mean age of 23 years. Four patients had received no previous treatment and one underwent previous ureterosigmoidostomy. Work-up included evaluation of upper tract and bladder biopsy. Bladder patch condition was variable. Surgery involved bladder preservation in the three patients who underwent primary repair, including bladder closure, bladder neck reconstruction and epispadias repair; two of them also had augmentation ileocystoplasty. The remaining two patients underwent ureterosigmoidostomy, cystectomy and epispadias repair. Abdominal wall closure was by fasciocutaneous M-plasty. Osteotomy was not done in any case.

RESULTS

In patients with bladder preservation, one patient was continent (>3 h) and voided normally whereas the other two showed day and night continence (2-3 h) with mild stress incontinence. Patients were satisfied with functional outcome. Ultrasound and intravenous pyelography showed preservation of upper tract. Follow-up period ranged from 1 to 8 years.

CONCLUSION

Patients with bladder exstrophy presenting in adulthood should not be denied the opportunity of primary reconstruction with bladder preservation in the absence of significant histological changes in the bladder mucosa.

摘要

目的

报告我们在成人经典膀胱外翻治疗方面的经验。

患者和方法

1977 年至 2006 年间,我们治疗了 5 例成年男性经典膀胱外翻-尿道上裂复合畸形患者。患者就诊时的年龄为 17 至 30 岁,平均 23 岁。其中 4 例患者未接受过任何治疗,1 例曾行输尿管乙状结肠吻合术。检查包括上尿路和膀胱活检。膀胱修补片的情况各不相同。手术包括 3 例患者的膀胱保留,包括膀胱关闭、膀胱颈部重建和尿道上裂修复;其中 2 例还进行了回肠膀胱扩大术。另外 2 例患者行输尿管乙状结肠吻合术、膀胱切除术和尿道上裂修复术。腹壁关闭采用筋膜皮瓣 M 成形术。在任何情况下都未进行骨切开术。

结果

在保留膀胱的患者中,1 例患者有控尿能力(>3 小时)并能正常排尿,另 2 例患者有白天和夜间控尿能力(2-3 小时),仅有轻度压力性尿失禁。患者对功能结果满意。超声和静脉肾盂造影显示上尿路保存良好。随访时间 1 至 8 年。

结论

在没有膀胱黏膜明显组织学改变的情况下,对于成年出现的膀胱外翻患者,不应拒绝行膀胱保留的一期重建手术机会。

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