Research Unit in Systemic Autoimmune Diseases, Vall D'hebron Research Institute, Hospital Vall D'hebron, Barcelona, Spain.
Autoimmun Rev. 2012 Dec;12(2):235-40. doi: 10.1016/j.autrev.2012.07.009. Epub 2012 Jul 13.
The Churg-Strauss Syndrome is an ANCA-associated vasculitis, an inflammatory multisystem disease with preference to the respiratory tract. Peripheral and tissue eosinophilia are the pathological hallmarks of this condition. The etiopathogenesis is unknown but some cytokines appear to play a central role and could be targets for new therapies.
变应性肉芽肿性血管炎是一种与抗中性粒细胞胞浆抗体（ANCA）相关的血管炎，是一种偏好呼吸道的炎症性多系统疾病。外周血和组织嗜酸性粒细胞增多是这种疾病的病理标志。其病因和发病机制尚不清楚，但一些细胞因子似乎起着核心作用，可能成为新疗法的靶点。
