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日本基于人群队列的症状性腰椎椎管狭窄症的患病率及其与身体机能表现的相关性:和歌山脊柱研究。

Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: the Wakayama Spine Study.

机构信息

Wakayama Medical University, Wakayama City, Japan.

出版信息

Osteoarthritis Cartilage. 2012 Oct;20(10):1103-8. doi: 10.1016/j.joca.2012.06.018. Epub 2012 Jul 10.

DOI:10.1016/j.joca.2012.06.018
PMID:22796511
Abstract

OBJECTIVE

The purpose of this study was to investigate the prevalence of symptomatic lumbar spinal stenosis (LSS) and to clarify the association between symptomatic LSS and physical performance using magnetic resonance imaging (MRI) in a population-based cohort.

DESIGN

This cross-sectional study was performed as a part of the research on osteoarthritis/osteoporosis against disability (ROAD) in Japan and 1,009 subjects (335 men, 674 women, mean age 66.3 years, age range 21-97 years) were analyzed. An experienced orthopedic surgeon obtained the medical history and performed the physical testing for all participants. Symptomatic LSS diagnostic criteria required the presence of both symptoms and radiographic LSS findings. A 6-m walking time, chair standing time, and one-leg standing time were obtained from all participants.

RESULTS

The prevalence of symptomatic LSS was 9.3% (95% confidence interval [CI]: 7.7-11.3) overall, 10.1% (CI: 7.4-13.8) in men and 8.9% (CI: 7.0-11.3) in women. There was a difference in the prevalence with increasing age by gender. The LSS prevalence showed little difference with age greater than 70 years for men, but the LSS prevalence for women was higher with increasing age. Among physical performance measures, 6-m walking time at a maximal pace was significantly associated with symptomatic LSS (P = 0.03).

CONCLUSION

The prevalence of symptomatic LSS was approximately 10% in a cohort resembling the general Japanese population. A 6-m walking time at a maximal pace was a more sensitive index than walking at a usual pace in assessing decreased physical performance associated with symptomatic LSS.

摘要

目的

本研究旨在调查基于人群的队列中症状性腰椎椎管狭窄症(LSS)的患病率,并使用磁共振成像(MRI)阐明症状性 LSS 与身体表现之间的关系。

设计

本横断面研究是日本骨关节炎/骨质疏松症防治(ROAD)研究的一部分,共分析了 1009 名受试者(335 名男性,674 名女性,平均年龄 66.3 岁,年龄范围 21-97 岁)。一名经验丰富的骨科医生为所有参与者获取病史并进行体格检查。症状性 LSS 的诊断标准要求存在症状和影像学 LSS 表现。所有参与者均获得 6 米步行时间、椅站时间和单腿站立时间。

结果

症状性 LSS 的总体患病率为 9.3%(95%置信区间[CI]:7.7-11.3),男性为 10.1%(CI:7.4-13.8),女性为 8.9%(CI:7.0-11.3)。按性别和年龄划分,患病率存在差异。男性 70 岁以上时,LSS 的患病率随年龄增长差异不大,但女性的 LSS 患病率随年龄增长而升高。在身体表现测量中,最大速度的 6 米步行时间与症状性 LSS 显著相关(P = 0.03)。

结论

与一般日本人群相似的队列中,症状性 LSS 的患病率约为 10%。在评估与症状性 LSS 相关的身体表现下降时,最大速度的 6 米步行时间比通常速度的步行时间更敏感。

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