Wakayama Medical University, Wakayama, Japan.
Osteoarthritis Cartilage. 2013 Jun;21(6):783-8. doi: 10.1016/j.joca.2013.02.656. Epub 2013 Mar 5.
Many asymptomatic individuals have radiographic lumbar spinal stenosis (LSS), but the prevalence of symptoms among individuals with radiographic LSS has not yet been established. The purpose of this study was to clarify the association between radiographic LSS and clinical symptoms in the general population.
In this cross-sectional study, data from 938 participants (308 men, 630 women; mean age, 66.3 years; range, 40-93 years) were analyzed. The severity of radiographic LSS, including central stenosis, lateral stenosis, and foraminal stenosis, was assessed by mobile magnetic resonance imaging and rated qualitatively. Assessment of clinical symptoms was based on the definition of symptomatic LSS in the North American Spine Society guideline.
We found that 77.9% of participants had more than moderate central stenosis and 30.4% had severe central stenosis. Logistic regression analysis after adjustment for age, sex, body mass index, and severity of radiographic LSS showed that severe central stenosis was related to clinical symptoms. However, only 17.5% of the participants with severe central stenosis were symptomatic.
Although radiographic LSS was common in our cohort, which resembled the general Japanese population, symptomatic persons were relatively uncommon.
许多无症状个体存在放射学腰椎椎管狭窄症（LSS），但放射学 LSS 个体出现症状的患病率尚未确定。本研究旨在阐明普通人群中放射学 LSS 与临床症状之间的关系。
在这项横断面研究中，分析了 938 名参与者（308 名男性，630 名女性；平均年龄 66.3 岁；范围为 40-93 岁）的数据。通过移动磁共振成像评估放射学 LSS 的严重程度，包括中央狭窄、侧方狭窄和椎间孔狭窄，并进行定性评估。临床症状的评估基于北美脊柱学会指南中对有症状 LSS 的定义。
我们发现，77.9%的参与者存在中度以上中央狭窄，30.4%存在严重中央狭窄。调整年龄、性别、体重指数和放射学 LSS 严重程度后进行的 logistic 回归分析显示，严重中央狭窄与临床症状有关。然而，仅有 17.5%的严重中央狭窄患者出现症状。
尽管我们的队列类似于一般的日本人群，放射学 LSS 很常见，但出现症状的患者相对较少。
