Zang Yachen, Xue Boxin, Zhang Yuanyuan, Yang Dongrong, Gao Jie, Sun Chuanyang, Cui Yong, Tao Wei, Chen Dong, Shan Yuxi
Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Urol Int. 2012;89(2):203-7. doi: 10.1159/000339608. Epub 2012 Jul 13.
To evaluate the 3-year clinical outcomes and durability of photoselective vaporization of the prostate (PVP) with the GreenLight HPS laser in the treatment of symptomatic and obstructive benign prostatic hyperplasia (BPH).
A total of 78 patients underwent PVP with the GreenLight HPS laser from October 2007 to November 2008. The baseline and treatment outcomes after surgery were evaluated 3 years later with the International Prostate Symptom Score (IPSS), quality of life (QoL), maximum flow rate (Q(max)), postvoid residual rate (PVR), and transrectal ultrasound-determined prostate volume. These parameters were assessed at 1, 3, 6, 12, 24, and 36 months.
Patients' urinary symptoms and QoL significantly improved after surgery. The functional outcomes showed immediate and stable improvements during the entire follow-up period. At 36 months, the average percentage of improvements compared with baseline was as follows: IPSS, 60.2%; QoL, 80.9%; Q(max), 138.7%, and PVR, 82.6%. The median prostate volume, evaluated by transrectal ultrasonography, showed a 50.4% reduction when compared to preoperative volume. Overall, complications from surgery were low; only 6.7% of the 75 patients required reoperation during the 3-year follow-up.
PVP using the GreenLight HPS laser showed a safe and effective treatment outcome for the treatment of symptomatic and obstructive BPH.
评估采用绿激光高功率选择性光汽化术（PVP）联合绿激光HPS激光治疗有症状的梗阻性良性前列腺增生（BPH）的3年临床疗效及耐用性。
2007年10月至2008年11月，共有78例患者接受了绿激光HPS激光的PVP治疗。3年后，采用国际前列腺症状评分（IPSS）、生活质量（QoL）、最大尿流率（Q(max)）、残余尿量率（PVR）和经直肠超声测定的前列腺体积对手术前后的基线和治疗结果进行评估。这些参数在1、3、6、12、24和36个月时进行评估。
术后患者的尿路症状和生活质量显著改善。功能结果在整个随访期间显示出即时且稳定的改善。在36个月时，与基线相比的平均改善百分比如下：IPSS为60.2%；QoL为80.9%；Q(max)为138.7%，PVR为82.6%。经直肠超声评估的前列腺体积中位数与术前体积相比减少了50.4%。总体而言，手术并发症发生率较低；在75例患者中，只有6.7%在3年随访期间需要再次手术。
使用绿激光HPS激光的PVP对有症状的梗阻性BPH治疗显示出安全有效的治疗效果。
