Li Zhaoyi, Hou Ruipeng, Li Jian
Department of Urology, The Union Medical Center of Tianjin, Tianjin, 300121, China.
Int Urol Nephrol. 2014 Apr;46(4):691-4. doi: 10.1007/s11255-013-0572-2. Epub 2013 Oct 5.
We compared the safety and efficacy of simultaneous transurethral GreenLight photoselective vaporization of bladder tumor and prostate (PVBT/PVP) in patients with bladder tumor and bladder outlet obstruction caused by benign prostate hyperplasia (BPH).
Sixty-two patients with bladder tumor were enrolled in our prospective and randomized trial. A total of 37 men underwent simultaneous transurethral PVBT/PVP, and 25 patients underwent PVBT alone. The clinicopathological parameters and the recurrence of bladder tumor on the bladder neck/prostatic fossa were evaluated in all patients.
Clinicopathological parameters of both groups were similar. The rates of recurrence, progression and tumor recurrence of bladder neck/prostatic fossa were 16.0, 4.0 and 4.0 % in the simultaneous resection group, and 18.9, 5.4 and 8.1 % in the group PVBT, respectively. No statistically significant differences were found between the two groups (P > 0.05).
Simultaneous PVBT/PVP may help decrease the overall recurrence rate and tumor recurrence in bladder neck/prostatic fossa. PVBT/PVP can be performed effectively and safely in patients with bladder tumor and BPH.
我们比较了在患有膀胱肿瘤且因良性前列腺增生（BPH）导致膀胱出口梗阻的患者中，同期经尿道膀胱肿瘤与前列腺绿激光选择性汽化术（PVBT/PVP）的安全性和有效性。
62例膀胱肿瘤患者纳入我们的前瞻性随机试验。共有37例男性接受了同期经尿道PVBT/PVP，25例患者仅接受了PVBT。评估了所有患者的临床病理参数以及膀胱颈/前列腺窝处膀胱肿瘤的复发情况。
两组的临床病理参数相似。同期切除组膀胱颈/前列腺窝处的复发率、进展率和肿瘤复发率分别为16.0%、4.0%和4.0%，PVBT组分别为18.9%、5.4%和8.1%。两组之间未发现统计学显著差异（P>0.05）。
同期PVBT/PVP可能有助于降低膀胱颈/前列腺窝处的总体复发率和肿瘤复发率。PVBT/PVP可在膀胱肿瘤和BPH患者中有效且安全地进行。
