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膀胱肿瘤合并下尿路症状患者同期经尿道绿激光膀胱肿瘤与前列腺光选择性汽化术的疗效与安全性

The efficacy and safety of simultaneous transurethral GreenLight photoselective vaporization of bladder tumor and prostate in patients with bladder tumor and lower urinary tract symptoms.

作者信息

Li Zhaoyi, Hou Ruipeng, Li Jian

机构信息

Department of Urology, The Union Medical Center of Tianjin, Tianjin, 300121, China.

出版信息

Int Urol Nephrol. 2014 Apr;46(4):691-4. doi: 10.1007/s11255-013-0572-2. Epub 2013 Oct 5.

Abstract

PURPOSE

We compared the safety and efficacy of simultaneous transurethral GreenLight photoselective vaporization of bladder tumor and prostate (PVBT/PVP) in patients with bladder tumor and bladder outlet obstruction caused by benign prostate hyperplasia (BPH).

METHODS

Sixty-two patients with bladder tumor were enrolled in our prospective and randomized trial. A total of 37 men underwent simultaneous transurethral PVBT/PVP, and 25 patients underwent PVBT alone. The clinicopathological parameters and the recurrence of bladder tumor on the bladder neck/prostatic fossa were evaluated in all patients.

RESULTS

Clinicopathological parameters of both groups were similar. The rates of recurrence, progression and tumor recurrence of bladder neck/prostatic fossa were 16.0, 4.0 and 4.0 % in the simultaneous resection group, and 18.9, 5.4 and 8.1 % in the group PVBT, respectively. No statistically significant differences were found between the two groups (P > 0.05).

CONCLUSIONS

Simultaneous PVBT/PVP may help decrease the overall recurrence rate and tumor recurrence in bladder neck/prostatic fossa. PVBT/PVP can be performed effectively and safely in patients with bladder tumor and BPH.

摘要

目的

我们比较了在患有膀胱肿瘤且因良性前列腺增生(BPH)导致膀胱出口梗阻的患者中,同期经尿道膀胱肿瘤与前列腺绿激光选择性汽化术(PVBT/PVP)的安全性和有效性。

方法

62例膀胱肿瘤患者纳入我们的前瞻性随机试验。共有37例男性接受了同期经尿道PVBT/PVP,25例患者仅接受了PVBT。评估了所有患者的临床病理参数以及膀胱颈/前列腺窝处膀胱肿瘤的复发情况。

结果

两组的临床病理参数相似。同期切除组膀胱颈/前列腺窝处的复发率、进展率和肿瘤复发率分别为16.0%、4.0%和4.0%,PVBT组分别为18.9%、5.4%和8.1%。两组之间未发现统计学显著差异(P>0.05)。

结论

同期PVBT/PVP可能有助于降低膀胱颈/前列腺窝处的总体复发率和肿瘤复发率。PVBT/PVP可在膀胱肿瘤和BPH患者中有效且安全地进行。

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