Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig-Holstein, Campus Kiel, Schwanenweg 21, 24105 Kiel, Germany.
Br J Anaesth. 2012 Sep;109(3):413-9. doi: 10.1093/bja/aes224. Epub 2012 Jul 12.
The intensified use of spinal anaesthesia (SPA) for Caesarean section significantly contributed to a decreased maternal mortality and morbidity. Nevertheless, one of the major side-effects is hypotension after SPA with potential negative effects on the fetus. Owing to discontinuous oscillometric measurements (non-invasive arterial pressure, NIAP), hypotensive episodes may be missed. Recently, a continuous NIAP measurement device (CNAP) with acceptable agreement with the mean invasive AP was introduced. We hypothesized that CNAP detects hypotensive episodes more reliably compared with NIAP measurements.
A total of 65 women undergoing Caesarean section under SPA were included in the study analysis. A total of 888 NIAP measurements obtained at 3 min cycles, starting from before SPA and continued until delivery, were analysed.
When averaged over all cycles, the lowest systolic AP identified by CNAP in each cycle [105 mm Hg, (24.4)] was significantly lower (P<0.001) than the average of the individual corresponding single NIAP measurements [126 mm Hg (22.1)] and highest CNAP average [126 mm Hg (24.5)]. Hypotension (systolic AP <100 mm Hg) was detected in 39% of all cycles with CNAP and in 9% with NIAP. Hypotension was detected in 91% of the patients based on CNAP and in 55% based on NIAP. Fetal acidosis defined by an umbilical vein pH under 7.25 did not occur when the lowest systolic AP measured by CNAP was above 100 mm Hg.
The CNAP device detected more hypotensive episodes after SPA and significantly lower AP compared with NIAP. AP monitoring based on CNAP may improve haemodynamic management in this patient population with potential benefit for the fetus.
椎管内麻醉(SPA)在剖宫产术中的强化使用显著降低了产妇的死亡率和发病率。然而,其主要副作用之一是 SPA 后低血压,可能对胎儿产生负面影响。由于间断的示波测量(无创动脉压,NIAP),可能会错过低血压发作。最近,一种与平均有创动脉压具有可接受一致性的连续 NIAP 测量设备(CNAP)被引入。我们假设 CNAP 比 NIAP 测量更可靠地检测到低血压发作。
本研究共纳入 65 例接受 SPA 剖宫产的妇女。分析了 SPA 前开始并持续至分娩的 3 分钟周期内共 888 次 NIAP 测量。
当平均所有周期时,CNAP 在每个周期中识别的最低收缩压 [105mmHg,(24.4)]明显低于(P<0.001)个体相应单次 NIAP 测量的平均值 [126mmHg,(22.1)]和最高 CNAP 平均值 [126mmHg,(24.5)]。CNAP 检测到 39%的周期存在低血压(收缩压<100mmHg),NIAP 检测到 9%的周期存在低血压。91%的患者根据 CNAP 检测到低血压,55%的患者根据 NIAP 检测到低血压。当 CNAP 测量的最低收缩压高于 100mmHg 时,脐静脉 pH 值低于 7.25 定义的胎儿酸中毒并未发生。
CNAP 设备在 SPA 后检测到更多的低血压发作,并且 AP 明显低于 NIAP。基于 CNAP 的 AP 监测可能会改善该患者群体的血流动力学管理,从而可能对胎儿有益。