弥漫性特发性神经内分泌细胞增生症：导致呼吸困难和肺结节的罕见病因。
Diffuse idiopathic neuroendocrine cell hyperplasia: an unusual cause of breathlessness and pulmonary nodules.
作者信息
Tippett V M, Wathen C G
机构信息
Department of Respiratory Medicine, Wycombe Hospital, High Wycombe, UK.
出版信息
BMJ Case Rep. 2010 Dec 1;2010:bcr0520103006. doi: 10.1136/bcr.05.2010.3006.
Abstract
A 66-year-old woman presented with dry cough and subsequent intermittent breathlessness and wheeze. During this time she was treated by her general practitioner for chronic obstructive pulmonary disease. When her symptoms worsened and her lung function had deteriorated, a high resolution CT scan was undertaken. This showed bilateral fine nodules. Investigations did not support a diagnosis of vasculitis and sarcoidosis was suspected. A lung biopsy was performed that showed diffuse idiopathic neuroendocrine cell hyperplasia. At follow-up, to date, the patient remains symptomatic but has not progressed or developed a carcinoid tumour.
摘要
一名66岁女性出现干咳，随后间歇性呼吸急促和喘息。在此期间，她的全科医生对其进行了慢性阻塞性肺疾病的治疗。当她的症状恶化且肺功能下降时，进行了高分辨率CT扫描。扫描显示双侧有小结节。检查结果不支持血管炎的诊断，怀疑为结节病。进行了肺活检，结果显示为弥漫性特发性神经内分泌细胞增生。截至随访时，患者仍有症状，但病情未进展，也未发展为类癌肿瘤。
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