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眼部带状疱疹继发的眼肌麻痹。

Ophthalmoplegia secondary to herpes zoster ophthalmicus.

作者信息

Ugarte Marta, Dey Sarju, Jones Carole A

机构信息

Manchester Academic Health Sciences Centre and NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester, UK.

出版信息

BMJ Case Rep. 2010 Nov 19;2010:bcr1220092532. doi: 10.1136/bcr.12.2009.2532.

Abstract

An 80-year-old Caucasian woman had been diagnosed with right herpes zoster ophthalmicus 2 ½ weeks before presentation to our department. Ten days after stopping oral aciclovir, she presented with periorbital pain, visual loss, ptosis and complete ophthalmoplegia. On examination, visual acuity in her right eye was hand movements, with a relative afferent pupillary defect and 2 mm proptosis. MRI demonstrated contrast enhancement within the orbit extending into the apex, suggestive of an inflammatory process. Oral treatment was started with oral aciclovir and corticosteroids for 2 months, when she had resolution of the optic neuropathy and ophthalmoplegia. Vision recovered to 6/9 and repeat neuroimaging revealed regression of the inflammatory process.

摘要

一名80岁的白种女性在到我们科室就诊前2.5周被诊断为右眼带状疱疹性眼炎。停用口服阿昔洛韦10天后,她出现眶周疼痛、视力丧失、上睑下垂和完全性眼肌麻痹。检查发现,她右眼的视力为手动,伴有相对传入性瞳孔障碍和眼球突出2毫米。磁共振成像(MRI)显示眼眶内有对比增强,延伸至眶尖,提示有炎症过程。开始口服阿昔洛韦和皮质类固醇进行治疗,持续2个月,之后她的视神经病变和眼肌麻痹得到缓解。视力恢复到6/9,重复神经影像学检查显示炎症过程消退。

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本文引用的文献

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Post herpetic neuralgia, schwann cell activation and vitamin D.带状疱疹后神经痛、许旺细胞激活与维生素 D
Med Hypotheses. 2009 Dec;73(6):927-9. doi: 10.1016/j.mehy.2009.06.039. Epub 2009 Jul 26.
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Clin Exp Dermatol. 2007 Mar;32(2):162-4. doi: 10.1111/j.1365-2230.2006.02296.x. Epub 2006 Nov 27.
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Orbital apex syndrome.眶尖综合征。
Curr Opin Ophthalmol. 2004 Dec;15(6):490-8. doi: 10.1097/01.icu.0000144387.12739.9c.

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