Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, 637371 Singapore.
J Am Chem Soc. 2012 Oct 24;134(42):17346-9. doi: 10.1021/ja305352d. Epub 2012 Jul 20.
Squaraine dyes were loaded inside mesoporous silica nanoparticles, and the nanoparticle surfaces were then wrapped with ultrathin graphene oxide sheets, leading to the formation of a novel hybrid material. The hybrid exhibits remarkable stability and can efficiently protect the loaded dye from nucleophilic attack. The biocompatible hybrid is noncytotoxic and presents significant potential for application in fluorescence imaging in vitro.
吖嗪染料被装载到介孔硅纳米粒子中，然后在纳米粒子表面包裹上超薄的氧化石墨烯片，形成了一种新型的杂化材料。该杂化材料具有显著的稳定性，能够有效地保护负载的染料免受亲核攻击。这种具有生物相容性的杂化材料无细胞毒性，在体外荧光成像方面具有很大的应用潜力。
