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经干扰素处理的细胞产生低感染性的水疱性口炎病毒。

Production of vesicular stomatitis virus with low infectivity by interferon-treated cells.

作者信息

Maheshwari R K, Friedman R M

出版信息

J Gen Virol. 1979 Jul;44(1):261-4. doi: 10.1099/0022-1317-44-1-261.

DOI:10.1099/0022-1317-44-1-261
PMID:227998
Abstract

In cultures of Ly cells treated with 10 or 30 reference units/ml of mouse interferon there was a 30 to 200 times reduction in the production of infectious vesicular stomatitis virus (VSV); virus particle production, as measured by VSV particle associated virus RNA, virus protein, and virus transcriptase, was inhibited by, at most, six times. These results suggested that interferon-treated cells produce VSV particles with low infectivity and resemble the findings in interferon-treated cells infected with murine leukaemia viruses.

摘要

在用10或30个参考单位/毫升小鼠干扰素处理的Ly细胞培养物中,传染性水泡性口炎病毒(VSV)的产生减少了30至200倍;通过VSV颗粒相关病毒RNA、病毒蛋白和病毒转录酶测量的病毒颗粒产生,最多被抑制6倍。这些结果表明,经干扰素处理的细胞产生感染性低的VSV颗粒,这与用鼠白血病病毒感染的经干扰素处理的细胞中的发现相似。

相似文献

1
Production of vesicular stomatitis virus with low infectivity by interferon-treated cells.经干扰素处理的细胞产生低感染性的水疱性口炎病毒。
J Gen Virol. 1979 Jul;44(1):261-4. doi: 10.1099/0022-1317-44-1-261.
2
Selective inhibition of glycoprotein and membrane protein of vesicular stomatitis virus from interferon-treated cells.对来自经干扰素处理细胞的水疱性口炎病毒糖蛋白和膜蛋白的选择性抑制。
Science. 1980 Feb 1;207(4430):540-1. doi: 10.1126/science.6243416.
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Effect of interferon treatment on vesicular stomatitis virus (VSV): release of unusual particles with low infectivity.干扰素治疗对水疱性口炎病毒(VSV)的影响:释放出感染性低的异常颗粒。
Virology. 1980 Mar;101(2):399-407. doi: 10.1016/0042-6822(80)90453-5.
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Interferon-treated cells release vesicular stomatitis virus particles lacking glycoprotein spikes: correlation with biochemical data.经干扰素处理的细胞释放缺乏糖蛋白刺突的水疱性口炎病毒颗粒:与生化数据的相关性。
Proc Natl Acad Sci U S A. 1980 Apr;77(4):2284-7. doi: 10.1073/pnas.77.4.2284.
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Cell killing by viruses. III. The interferon system and inhibition of cell killing by vesicular stomatitis virus.病毒导致的细胞杀伤。III. 干扰素系统与水泡性口炎病毒对细胞杀伤的抑制作用。
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Inhibition of vesicular stomatitis virus by kethoxal bis (thiosemicarbazone).酮醛双(硫代氨基脲)对水疱性口炎病毒的抑制作用
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Overproduction of double-stranded RNA in vesicular stomatitis virus-infected cells activates a constitutive cell-type-specific antiviral response.水泡性口炎病毒感染的细胞中双链RNA的过量产生激活了一种组成型细胞类型特异性抗病毒反应。
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Differential sensitivity of Rauscher murine leukaemia virus (MuLV-R) to interferons in two interferon-responsive cell lines.劳氏鼠白血病病毒(MuLV-R)在两种干扰素应答细胞系中对干扰素的敏感性差异
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Effect of interferon on transcription and translation of vesicular stomatitis virus in human and simian cell cultures.干扰素对人及猴细胞培养中水泡性口炎病毒转录和翻译的影响。
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Morphological and biochemical characterization of vesicular stomatitis virus with low infectivity released from interferon treated cells.从经干扰素处理的细胞中释放的低感染性水疱性口炎病毒的形态学和生化特征
Uttar Pradesh State Dent J. 1980 Jul;11(3):95-110.

引用本文的文献

1
IFN-dependent and -independent reduction in West Nile virus infectivity in human dermal fibroblasts.IFN 依赖性和非依赖性降低人皮肤成纤维细胞中的西尼罗河病毒感染性。
Viruses. 2014 Mar 24;6(3):1424-41. doi: 10.3390/v6031424.
2
Brefeldin A inhibits the antiviral action of interferon against encephalomyocarditis virus.布雷菲德菌素A抑制干扰素对脑心肌炎病毒的抗病毒作用。
Virus Res. 1996 Feb;40(2):123-33. doi: 10.1016/0168-1702(95)01262-1.
3
Interferon-treated cells release vesicular stomatitis virus particles lacking glycoprotein spikes: correlation with biochemical data.
经干扰素处理的细胞释放缺乏糖蛋白刺突的水疱性口炎病毒颗粒:与生化数据的相关性。
Proc Natl Acad Sci U S A. 1980 Apr;77(4):2284-7. doi: 10.1073/pnas.77.4.2284.
4
Use of Brefeldin A to localize block in intracellular transport of vesicular stomatitis virus G protein on interferon-treated cells.使用布雷菲德菌素A定位水泡性口炎病毒G蛋白在干扰素处理细胞内的转运阻滞。
Arch Virol. 1992;124(1-2):171-9. doi: 10.1007/BF01314635.
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Loss of infectivity by progeny virus from alpha interferon-treated human immunodeficiency virus type 1-infected T cells is associated with defective assembly of envelope gp120.来自α干扰素处理的1型人类免疫缺陷病毒感染的T细胞的子代病毒感染力丧失与包膜糖蛋白gp120组装缺陷有关。
J Virol. 1992 Dec;66(12):7543-8. doi: 10.1128/JVI.66.12.7543-7548.1992.