Hematology Center, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing 100045, China.
Chin Med J (Engl). 2012 May;125(9):1675-6.
Clinical categories of Langerhans cell histiocytosis (LCH) include single and multi-system disease. Pulmonary LCH is rare, which is an unusual interstitial lung disease with the characteristics of monoclonal proliferation and infiltration of Langerhans' cells to organs. We report our experience of a rare LCH case of multiple organs such as pulmonary and liver as the main clinical manifestation. The patient was treated with chemotherapy which included prednisone, vinblastine, methotrexate and 6-mercaptopurine for 52 weeks and follow up all along. The patient has a favorable clinical outcome.
郎格汉斯细胞组织细胞增生症（LCH）的临床分类包括单系统疾病和多系统疾病。肺部 LCH 较为罕见，是一种非 常的间质性肺疾病，其特征是朗格汉斯细胞的单克隆增殖和浸润到器官中。我们报告了一例以肺部和肝脏等多器官为主要临床表现的罕见 LCH 病例。该患者接受了包括泼尼松、长春新碱、甲氨蝶呤和 6-巯基嘌呤在内的化疗，共治疗 52 周，并一直进行随访。患者的临床结局良好。
