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[心肌梗死后心绞痛行冠状动脉旁路移植术的远期结果——与术前心肌梗死面积的关系]

[Late results of CABG for postinfarction angina--relation to preoperative myocardial infarct size].

作者信息

Takahashi T, Nakano S, Matsuda H, Taniguchi K, Matsumura R, Hirata N, Sakakibara T, Sakai K, Hirose H, Kawashima Y

机构信息

First Department of Surgery, Osaka University Medical School, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1990 Nov;38(11):2208-14.

PMID:2280093
Abstract

We evaluated the late results of coronary bypass grafting (CABG) in 85 patients. The patients were divided into two groups according to preoperative MI size estimated by the Selvester QRS score; 24 with MI size of larger than 20% of LV muscle (group A; average 28 +/- 11%), and 61 with MI size smaller than 20% (group B; average 10 +/- 9%). New York Heart Association classes of both groups following CABG improved significantly (from 2.8 +/- 0.7 to 1.3 +/- 0.4 in group A; p less than 0.01, from 2.5 +/- 0.6 to 1.2 +/- 0.5 in group B; p less than 0.01). There was higher incidence of serious ventricular arrhythmias in group A than in group B (83% vs. 21%, p less than 0.01). In Group A, LVEF and LVESVI did not improve following CABG (from 17 +/- 9 to 16 +/- 8 mmHg, from 39 +/- 15 to 40 +/- 15%, from 66 +/- 28 to 69 +/- 40 ml/M2), while in Group B, those improved significantly (from 13 +/- 6 to 11 +/- 5 mmHg; p less than 0.01, from 53 +/- 14 to 58 +/- 10%; p less than 0.01, from 39 +/- 23 to 32 +/- 14 ml/M2; p less than 0.05). The exercise-to-rest LVSWI ratios increased significantly following CABG in both groups (from 86 +/- 25 to 160 +/- 56% in group A; p less than 0.05, from 92 +/- 31 to 140 +/- 37% in group B; p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们评估了85例患者冠状动脉旁路移植术(CABG)的远期结果。根据塞尔维斯特QRS评分估计的术前心肌梗死面积将患者分为两组;24例心肌梗死面积大于左心室肌的20%(A组;平均28±11%),61例心肌梗死面积小于20%(B组;平均10±9%)。两组CABG术后纽约心脏协会心功能分级均显著改善(A组从2.8±0.7改善至1.3±0.4;p<0.01,B组从2.5±0.6改善至1.2±0.5;p<0.01)。A组严重室性心律失常的发生率高于B组(83%对21%,p<0.01)。在A组中,CABG术后左心室射血分数(LVEF)和左心室舒张末期容积指数(LVESVI)未改善(从17±9至16±8 mmHg,从39±15至40±15%,从66±28至69±40 ml/M2),而在B组中,这些指标显著改善(从13±6至11±5 mmHg;p<0.01,从53±14至58±10%;p<0.01,从39±23至32±14 ml/M2;p<0.05)。两组CABG术后运动与静息左心室每搏量指数(LVSWI)比值均显著增加(A组从86±25至160±56%;p<0.05,B组从92±31至140±37%;p<0.05)。(摘要截取自250字)

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