Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Curr Opin Support Palliat Care. 2012 Sep;6(3):386-90. doi: 10.1097/SPC.0b013e328356ab5e.
Awareness of palliative care, including knowledge and skills regarding symptom alleviation via pharmacological and non-pharmacological interventions, is limited in many settings. Lists have been published of recommended drugs for palliative care that include medications for different disease stages, using different modes of administration.
Recent studies confirm that many of the most common symptoms in dying patients, for example pain, dyspnoea, anxiety, nausea, and delirium, are similar regardless of diagnosis. The classes of drugs most commonly recommended for alleviation of these symptoms are opioids, neuroleptics, benzodiazepines, and antimuscarinic drugs. Other recommendations have the character of emergency kits of standard drugs for common symptoms, to be used when needed in caring for dying patients at home or in hospitals.
Recommendations for the most appropriate drugs which should be available for the care of dying patients in all settings is suggested to have potential to improve quality of care through increasing the confidence of physicians and nurses, being costeffective, decreasing the need for hospital admissions, and most of all - reducing suffering. Education and training at all levels, as well as further policy work through expert recommendations, care pathways, and media attention, are needed.
在许多情况下,人们对姑息治疗的认识有限,包括通过药物和非药物干预缓解症状的知识和技能。已经发布了姑息治疗推荐药物清单,其中包括针对不同疾病阶段的药物,以及不同的给药方式。
最近的研究证实,在临终患者中,许多最常见的症状,如疼痛、呼吸困难、焦虑、恶心和谵妄,无论诊断如何,都很相似。最常被推荐用于缓解这些症状的药物类别是阿片类药物、神经安定药、苯二氮䓬类药物和抗毒蕈碱药物。其他建议则是针对常见症状的标准药物急救包,以便在家庭或医院护理临终患者时按需使用。
建议在所有环境中为临终患者护理提供最合适的药物,这有可能通过提高医生和护士的信心、具有成本效益、减少住院需求,以及最重要的是减轻痛苦,从而提高护理质量。需要在各个层面进行教育和培训,以及通过专家建议、护理途径和媒体关注进一步制定政策。