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透析:腹膜透析患者的低钾血症与心脏风险。

Dialysis: Hypokalaemia and cardiac risk in peritoneal dialysis patients.

机构信息

Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, 30-32 Ngan Shing Street, Shatin, Hong Kong, China.

出版信息

Nat Rev Nephrol. 2012 Sep;8(9):501-3. doi: 10.1038/nrneph.2012.159. Epub 2012 Jul 17.

DOI:10.1038/nrneph.2012.159
PMID:22801950
Abstract

Dialysis, particularly haemodialysis, is associated with an increased risk of cardiovascular disease. A new study confirms that hypokalaemia confers an excess cardiovascular risk and contributes disproportionately to the high risk of death in patients on peritoneal dialysis, which may partially account for the fact that observed cardiac risk is similar for patients on peritoneal dialysis and haemodialysis.

摘要

透析,特别是血液透析,与心血管疾病风险增加有关。一项新的研究证实,低钾血症会带来额外的心血管风险,并不成比例地导致腹膜透析患者的死亡风险升高,这可能部分解释了观察到的腹膜透析和血液透析患者的心脏风险相似的原因。

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1
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Low Serum Potassium Levels and Clinical Outcomes in Peritoneal Dialysis-International Results from PDOPPS.

本文引用的文献

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Serum potassium and cause-specific mortality in a large peritoneal dialysis cohort.血清钾与大型腹膜透析队列的特定病因死亡率。
Clin J Am Soc Nephrol. 2012 Aug;7(8):1272-84. doi: 10.2215/CJN.00960112. Epub 2012 May 24.
2
New perspectives on blood pressure variability in hemodialysis patients.
Am J Kidney Dis. 2012 Mar;59(3):333-5. doi: 10.1053/j.ajkd.2012.01.003.
3
Dialysis outcomes and analysis of practice patterns suggests the dialysis schedule affects day-of-week mortality.透析结果和实践模式分析表明,透析时间安排会影响每周的死亡率。
腹膜透析患者低血清钾水平与临床结局——国际腹膜透析预后与实践模式研究(PDOPPS)的结果
Kidney Int Rep. 2020 Nov 22;6(2):313-324. doi: 10.1016/j.ekir.2020.11.021. eCollection 2021 Feb.
4
Time-averaged serum potassium levels and its fluctuation associate with 5-year survival of peritoneal dialysis patients: two-center based study.腹膜透析患者的时间平均血清钾水平及其波动与5年生存率相关:一项基于两个中心的研究。
Sci Rep. 2015 Oct 28;5:15743. doi: 10.1038/srep15743.
5
Low Serum Potassium Levels Increase the Infectious-Caused Mortality in Peritoneal Dialysis Patients: A Propensity-Matched Score Study.低血清钾水平增加腹膜透析患者感染所致死亡率:一项倾向匹配评分研究
PLoS One. 2015 Jun 19;10(6):e0127453. doi: 10.1371/journal.pone.0127453. eCollection 2015.
6
Serum potassium levels and its variability in incident peritoneal dialysis patients: associations with mortality.新入腹膜透析患者的血清钾水平及其变异性:与死亡率的关联
PLoS One. 2014 Jan 27;9(1):e86750. doi: 10.1371/journal.pone.0086750. eCollection 2014.
Kidney Int. 2012 Jun;81(11):1108-15. doi: 10.1038/ki.2011.481. Epub 2012 Feb 1.
4
Facility-level interpatient hemoglobin variability in hemodialysis centers participating in the Dialysis Outcomes and Practice Patterns Study (DOPPS): Associations with mortality, patient characteristics, and facility practices.参与 Dialysis Outcomes and Practice Patterns Study(DOPPS)的血液透析中心的患者间血红蛋白变异性与死亡率、患者特征和中心实践的关系:设施水平。
Am J Kidney Dis. 2011 Feb;57(2):266-75. doi: 10.1053/j.ajkd.2010.11.003.
5
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