妊娠相关的短暂性骨质疏松症：双膦酸盐类药物在哺乳期母亲治疗中的应用
Transient osteoporosis associated with pregnancy: use of bisphosphonate in treating a lactating mother.
作者信息
Shenker N G, Shaikh M F, Jawad A S M
机构信息
Department of Rheumatology, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK.
出版信息
BMJ Case Rep. 2010 Dec 14;2010:bcr0720092112. doi: 10.1136/bcr.07.2009.2112.
Abstract
Transient osteoporosis is a rare condition causing regional pain, immobility and functional compromise. The authors present the case of a pregnant lady with multiple sites of transient osteoporosis, including a stress fracture, successfully treated with intravenous pamidronate and a physical rehabilitation programme. The authors discuss the mechanisms for the syndrome and its overlap with complex regional pain syndrome type I; as well as the implications of bisphosphonate administration to a nursing mother. The authors also highlight the advantages of MRI over standard radiography when investigating unexplained foot pain.
摘要
短暂性骨质疏松症是一种罕见病症，可导致局部疼痛、活动受限和功能障碍。作者报告了一例患有多处短暂性骨质疏松症（包括应力性骨折）的孕妇病例，该患者通过静脉注射帕米膦酸盐和物理康复计划成功治愈。作者讨论了该综合征的发病机制及其与I型复杂性区域疼痛综合征的重叠情况；以及双膦酸盐给药对哺乳期母亲的影响。作者还强调了在调查不明原因的足部疼痛时，磁共振成像（MRI）相对于标准X线摄影的优势。
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Arthroscopy. 2006 Aug;22(8):866-71. doi: 10.1016/j.arthro.2006.04.095.
2
Effective and rapid treatment of painful localized transient osteoporosis (bone marrow edema) with intravenous ibandronate.静脉注射伊班膦酸钠有效且快速治疗疼痛性局限性短暂性骨质疏松症（骨髓水肿）
Osteoporos Int. 2005 Dec;16(12):2063-8. doi: 10.1007/s00198-005-2001-6. Epub 2005 Oct 14.
3
Successful neridronate therapy in transient osteoporosis of the hip.
Clin Rheumatol. 2005 Feb;24(1):67-9. doi: 10.1007/s10067-004-0957-9. Epub 2004 Aug 19.
4
Taking bisphosphonates during pregnancy.孕期服用双膦酸盐类药物。
Can Fam Physician. 2003 Oct;49:1281-2.
5
Transitory demineralization of the hip in pregnancy. A report of three cases.孕期髋关节短暂性脱矿质化。三例报告。
J Bone Joint Surg Am. 1959 Oct;41-A:1327-33.
6
Biochemical markers of bone metabolism in bone marrow edema syndrome of the hip.髋部骨髓水肿综合征中骨代谢的生化标志物。
Bone. 2003 Sep;33(3):346-51. doi: 10.1016/s8756-3282(03)00164-9.
7
Calcitonin in the treatment of transient osteoporosis of the hip.
Semin Arthritis Rheum. 2003 Jun;32(6):388-97. doi: 10.1053/sarh.2002.50014.
8
Intravenous pamidronate for treatment of reflex sympathetic dystrophy during breast feeding.
J Bone Miner Res. 2000 Oct;15(10):2052-5. doi: 10.1359/jbmr.2000.15.10.2052.
9
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Am J Phys Med Rehabil. 1998 Mar-Apr;77(2):153-6.
10
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Clin Orthop Relat Res. 1997 Jan(334):73-84.
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