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妊娠相关的短暂性骨质疏松症:双膦酸盐类药物在哺乳期母亲治疗中的应用

Transient osteoporosis associated with pregnancy: use of bisphosphonate in treating a lactating mother.

作者信息

Shenker N G, Shaikh M F, Jawad A S M

机构信息

Department of Rheumatology, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK.

出版信息

BMJ Case Rep. 2010 Dec 14;2010:bcr0720092112. doi: 10.1136/bcr.07.2009.2112.

Abstract

Transient osteoporosis is a rare condition causing regional pain, immobility and functional compromise. The authors present the case of a pregnant lady with multiple sites of transient osteoporosis, including a stress fracture, successfully treated with intravenous pamidronate and a physical rehabilitation programme. The authors discuss the mechanisms for the syndrome and its overlap with complex regional pain syndrome type I; as well as the implications of bisphosphonate administration to a nursing mother. The authors also highlight the advantages of MRI over standard radiography when investigating unexplained foot pain.

摘要

短暂性骨质疏松症是一种罕见病症,可导致局部疼痛、活动受限和功能障碍。作者报告了一例患有多处短暂性骨质疏松症(包括应力性骨折)的孕妇病例,该患者通过静脉注射帕米膦酸盐和物理康复计划成功治愈。作者讨论了该综合征的发病机制及其与I型复杂性区域疼痛综合征的重叠情况;以及双膦酸盐给药对哺乳期母亲的影响。作者还强调了在调查不明原因的足部疼痛时,磁共振成像(MRI)相对于标准X线摄影的优势。

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