Adolescent Breast Clinic, Children's Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA.
Pediatrics. 2012 Aug;130(2):e339-46. doi: 10.1542/peds.2011-3869. Epub 2012 Jul 16.
To determine the physical and psychosocial impact of macromastia on adolescents considering reduction mammaplasty in comparison with healthy adolescents.
The following surveys were administered to adolescents with macromastia and control subjects, aged 12 to 21 years: Short-Form 36v2, Rosenberg Self-Esteem Scale, Breast-Related Symptoms Questionnaire, and Eating-Attitudes Test-26 (EAT-26). Demographic variables and self-reported breast symptoms were compared between the 2 groups. Linear regression models, unadjusted and adjusted for BMI category (normal weight, overweight, obese), were fit to determine the effect of case status on survey score. Odds ratios for the risk of disordered eating behaviors (EAT-26 score ≥ 20) in cases versus controls were also determined.
Ninety-six subjects with macromastia and 103 control subjects participated in this study. Age was similar between groups, but subjects with macromastia had a higher BMI (P = .02). Adolescents with macromastia had lower Short-Form 36v2 domain, Rosenberg Self-Esteem Scale, and Breast-Related Symptoms Questionnaire scores and higher EAT-26 scores compared with controls. Macromastia was also associated with a higher risk of disordered eating behaviors. In almost all cases, the impact of macromastia was independent of BMI category.
Macromastia has a substantial negative impact on health-related quality of life, self-esteem, physical symptoms, and eating behaviors in adolescents with this condition. These observations were largely independent of BMI category. Health care providers should be aware of these important negative health outcomes that are associated with macromastia and consider early evaluation for adolescents with this condition.
比较考虑乳房缩小术的巨乳症青少年与健康青少年，确定巨乳症对青少年的身体和心理社会影响。
对 12 至 21 岁的巨乳症青少年和对照组青少年进行以下调查：健康调查简表 36 项第 2 版（Short-Form 36v2）、罗森伯格自尊量表（Rosenberg Self-Esteem Scale）、乳房相关症状问卷（Breast-Related Symptoms Questionnaire）和饮食态度测试 26 项（Eating-Attitudes Test-26，EAT-26）。比较两组间的人口统计学变量和自我报告的乳房症状。对病例状态对调查评分的影响进行未调整和按体重指数类别（正常体重、超重、肥胖）调整的线性回归模型拟合。还确定了病例相对于对照组发生饮食障碍行为（EAT-26 评分≥20）的风险的比值比。
本研究共纳入 96 例巨乳症患者和 103 例对照组患者。两组年龄相似，但巨乳症患者的 BMI 较高（P=0.02）。与对照组相比，巨乳症青少年的 Short-Form 36v2 各领域评分、罗森伯格自尊量表评分和乳房相关症状问卷评分较低，EAT-26 评分较高。巨乳症也与饮食障碍行为的风险增加相关。在几乎所有情况下，巨乳症的影响独立于 BMI 类别。
巨乳症对患有该疾病的青少年的健康相关生活质量、自尊、身体症状和饮食行为有重大负面影响。这些观察结果在很大程度上独立于 BMI 类别。医疗保健提供者应意识到与巨乳症相关的这些重要的负面健康结果，并考虑对患有该疾病的青少年进行早期评估。
