Mechanisms of immune status disorders in chronic ethanol intoxication.
作者信息
Zabrodskii P F, Lim V G, Grishin V A, Kuzmin A V
机构信息
Saratov State Medical University, Russia.
出版信息
Bull Exp Biol Med. 2011 Nov;152(1):90-2. doi: 10.1007/s10517-011-1462-1.
PMID:22803049
Abstract
Experiments of outbred albino rats showed that chronic ethanol intoxication (20 days, summary dose 5 LD(50)) inhibited immune reactions mainly mediated by Th1-cells, increased blood corticosterone concentration, reduced T-lymphocyte acetylcholinesterase activity, blood concentrations of IFN-γ, IL-2, IL-4, IL-10, and increased IL-6 level.
摘要
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