肺表面活性物质对巨噬细胞形态和功能的体外作用。
In vitro effects of pulmonary surfactant on macrophage morphology and function.
作者信息
Lepekha L N, Alexandrova E A, Erokhina M V
机构信息
Institute of Tuberculosis, the Russian Academy of Medical Sciences, Moscow, Russia.
出版信息
Bull Exp Biol Med. 2012 Feb;152(4):489-93. doi: 10.1007/s10517-012-1560-8.
The effects of pulmonary surfactant on the morphology and functioning of young macrophages were studied on the model of monocyte/macrophage differentiation in vitro and on macrophages of the bronchial alveolar lavage fluid. Surfactant is not a differentiation inductor, but it stimulated the maturation and phagocytic activity of young macrophages. The stimulatory effect of surfactant on phagocytic activity of macrophages persisted even after its removal from the culture medium.
在体外单核细胞/巨噬细胞分化模型以及支气管肺泡灌洗液巨噬细胞上，研究了肺表面活性剂对年轻巨噬细胞形态和功能的影响。表面活性剂不是分化诱导剂，但它刺激了年轻巨噬细胞的成熟和吞噬活性。即使从培养基中去除表面活性剂后，其对巨噬细胞吞噬活性的刺激作用仍然存在。
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