正常条件和热损伤下大鼠肝脏醛脱氢酶：部分纯化及性质研究
Rat hepatic aldehyde dehydrogenase in normal conditions and thermal injury: partial purification, property investigation.
作者信息
Solovyeva A G, Zimin Yu V, Zaskanova A V
机构信息
Nizhny Novgorod Institute of Traumatology and Orthopedics, Federal Agency of High Technological Medical Care, Russia.
出版信息
Bull Exp Biol Med. 2012 Mar;152(5):575-7. doi: 10.1007/s10517-012-1578-y.
PMID:22803136
Abstract
Catalytical properties of aldehyde dehydrogenase were studied using preparations of this enzyme, obtained from control rats and rats with thermal injury. Aldehyde dehydrogenase was shown to participate in the metabolism of aromatic and aliphatic aldehydes. Kinetic characteristics of the enzyme with different substrates were studied under normal conditions and in thermal burn injury.
摘要
使用从对照大鼠和热损伤大鼠获得的该酶制剂，研究了醛脱氢酶的催化特性。结果表明，醛脱氢酶参与芳香族和脂肪族醛的代谢。在正常条件下和热烧伤损伤情况下，研究了该酶与不同底物的动力学特性。
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