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尼日利亚儿童可预防疾病发病率的十年回顾:扩大免疫规划(EPI)成效如何?最新情况

A 10-year review of morbidity from childhood preventable diseases in Nigeria: how successful is the expanded programme on immunization (EPI)? An update.

作者信息

Babaniyi O A

机构信息

Department of Epidemiology and Community Health, University of Ilorin Teaching Hospital, Kwara State, Nigeria.

出版信息

J Trop Pediatr. 1990 Dec;36(6):306-13. doi: 10.1093/tropej/36.6.306.

Abstract

Morbidity and mortality in children of developing countries are primarily due to preventable infectious diseases such as measles, poliomyelitis, tuberculosis, whooping cough, diphtheria, and tetanus. By 1990 WHO hopes to have every child in the world immunized against these six diseases, that was why the Expanded Programme on Immunization (EPI) was launched. In Nigeria, a nationwide execution of EPI began in 1979. In view of the huge population of Nigeria, an evaluation of the efficiency of the EPI programme at reducing morbidity and mortality from the six target diseases has national and global importance. One such analysis of disease trends showed that apart from tuberculosis and acute poliomyelitis there was no clear reduction in morbidity from the EPI target diseases between 1979 and 1983. The programme was revised and relaunched nationwide in 1984. This paper attempts to update documented programme achievements by including information on EPI diseases from 1974 to 1988. An analysis of available data shows that there has been clear reduction in morbidity from measles and whooping cough since 1986, and that the incidence of tuberculosis is on the increase from 1984, despite a national BCG coverage of over 80 per cent. It is suggested that future evaluations should include data on community-based surveys on poliomyelitis and neonatal tetanus, and use the technique of decision analysis to estimate EPI impact on mortality. A similar effort in this paper predicted a 42 per cent morbidity and 37 per cent mortality reductions from EPI target diseases in Nigeria by the end of 1989.

摘要

发展中国家儿童的发病和死亡主要归因于可预防的传染病,如麻疹、脊髓灰质炎、结核病、百日咳、白喉和破伤风。世界卫生组织希望到1990年让世界上每个儿童都接种针对这六种疾病的疫苗,这就是扩大免疫规划(EPI)启动的原因。在尼日利亚,1979年开始在全国范围内实施EPI。鉴于尼日利亚人口众多,评估EPI计划在降低六种目标疾病的发病率和死亡率方面的效率具有国家和全球意义。一项关于疾病趋势的分析表明,除了结核病和急性脊髓灰质炎外,1979年至1983年间EPI目标疾病的发病率没有明显下降。该计划于1984年进行修订并在全国重新启动。本文试图通过纳入1974年至1988年EPI疾病的信息来更新已记录的计划成果。对现有数据的分析表明,自1986年以来麻疹和百日咳的发病率明显下降,尽管全国卡介苗接种覆盖率超过80%,但结核病的发病率自1984年以来一直在上升。建议未来的评估应包括基于社区的脊髓灰质炎和新生儿破伤风调查数据,并使用决策分析技术来估计EPI对死亡率的影响。本文的一项类似研究预测,到1989年底,尼日利亚EPI目标疾病的发病率将降低42%,死亡率将降低37%。

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