[用色谱法检测工作场所空气中的异氟烷]

[Detecting the isoflurane in the air of workplaces with chromatographic method].

作者信息

Zhang Wen, Cai Jin-min, Li Tian-di, He Jun-tao, Li Shuang-feng, Yun Jian-pei, Lin Yi-ran, Yi Juan

机构信息

Shenzhen Prevention and Treatment Center for Occupational Diseases, Guangdong, China.

出版信息

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2012 May;30(5):382-4.

PMID:22804994

Abstract

OBJECTIVE

To establish a solvent desorption Gas chromatographic method for detecting the isoflurane in air of workplaces.

METHODS

This method is based on "Standardization of methods for determination of toxic substances in workplace air".

RESULTS

This method presents the linear relation with the minimum detectable limit 1.0 µg/ml and the minimum detectable concentration 0.07 mg/m(3). The precision (RSD) was 0.5% ∼ 5.0%, the mean dsorption efficiencies were 96.7% ∼ 98.9%, the absorption efficiencies were 92.1% ∼ 100%, the breakthrough volume was 3.7 mg isoflurane/100 mg active carbon. Other volatile organic solvents (Sevoflurane, Enflurane and Ethyl Alcohol) did not interfere the detection. The sample could be stored in the active carbon tube at least for 10 days.

CONCLUSION

This method is meet the requirement of GBZ/T 210.4-2008 "Guide for establishing occupational health standards-Part4: Determination methods of air chemicals in workplace" and is feasible for determining the isoflurane in the air of workplaces.

摘要

目的

建立工作场所空气中异氟烷的溶剂解吸气相色谱测定方法。

方法

本方法依据《工作场所空气中有害物质测定方法的标准化》。

结果

本方法线性关系良好，最低检出限为1.0μg/ml，最低检出浓度为0.07mg/m³。精密度（RSD）为0.5%～5.0%，平均解吸效率为96.7%～98.9%，吸收效率为92.1%～100%，穿透容量为3.7mg异氟烷/100mg活性炭。其他挥发性有机溶剂（七氟烷、恩氟烷和乙醇）不干扰测定。样品在活性炭管中至少可保存10天。