Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia 22908-1414, USA.
J Surg Oncol. 2012 Oct 1;106(5):575-9. doi: 10.1002/jso.23206. Epub 2012 Jul 17.
Primary aldosteronism is the most common form of secondary hypertension. Case detection is based on an abnormal plasma aldosterone:plasma renin activity ratio and the diagnosis must be confirmed with an aldosterone suppression test. Subtype differentiation should be performed using adrenal venous sampling. Approximately 50% of patients with primary aldosteronism will have a unilateral aldosterone-producing adenoma; laparoscopic adrenalectomy results in cure of hypertension in 60% and improvement in blood pressure control in the remainder.
原醛症是最常见的继发性高血压。病例检测基于异常的血浆醛固酮：血浆肾素活性比值，且必须通过醛固酮抑制试验来确诊。亚型分化应使用肾上腺静脉采样进行。大约 50%的原醛症患者会有单侧醛固酮分泌腺瘤；腹腔镜肾上腺切除术可使 60%的高血压患者治愈，其余患者的血压控制也有所改善。
