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对数转换:在生物医学研究中的应用和解释。

Log transformation: application and interpretation in biomedical research.

机构信息

Department of Biostatistics and Computational Biology, University of Rochester, Rochester, NY 14642, USA.

出版信息

Stat Med. 2013 Jan 30;32(2):230-9. doi: 10.1002/sim.5486. Epub 2012 Jul 16.

DOI:10.1002/sim.5486
PMID:22806695
Abstract

The log transformation has been widely used in biomedical research to deal with the skewed data. However, in the medical publications, we have found many misuses and misinterpretations of analysis based on log-transformed data. In this paper, we list some common scenarios of misuse and misinterpretation of log transformation in biomedical applications. We also provide both theoretical and practical justifications to support our viewpoints.

摘要

对数转换在处理偏态数据的生物医学研究中得到了广泛的应用。然而,在医学出版物中,我们发现许多基于对数转换后的数据进行分析的误用和误解。本文列出了生物医学应用中对数转换的一些常见误用和误解的场景。我们还提供了理论和实践的依据来支持我们的观点。

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Log transformation: application and interpretation in biomedical research.对数转换:在生物医学研究中的应用和解释。
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