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[(3R*,4R*,5R*)-2,3-二苯基异恶唑烷-4,5-二基]二甲醇

[(3R*,4R*,5R*)-2,3-Diphenyl-isoxazolidine-4,5-di-yl]dimethanol.

作者信息

Guner Selahaddin, Seftalicioglu Kűbra

机构信息

Kocaeli University, Faculty of Art and Science, Department of Chemistry, 41380, Kocaeli, Turkey.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2061. doi: 10.1107/S1600536812025032. Epub 2012 Jun 13.

DOI:10.1107/S1600536812025032
PMID:22807882
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3393325/
Abstract

In the title compound, C(17)H(19)NO(3), the isoxazolidine ring adopts an envelope conformation with the O atom as the flap. In the crystal, O-H⋯O hydrogen bonds form C(2) (3)(14) R(2) (2)(14) motifs.

摘要

在标题化合物C₁₇H₁₉NO₃中，异恶唑烷环呈信封式构象，以O原子为翻盖。在晶体中，O—H⋯O氢键形成C(2) (3)(14) R(2) (2)(14) 模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4156/3393325/bc4f96f92298/e-68-o2061-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4156/3393325/f564a8154531/e-68-o2061-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4156/3393325/bc4f96f92298/e-68-o2061-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4156/3393325/f564a8154531/e-68-o2061-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4156/3393325/bc4f96f92298/e-68-o2061-fig2.jpg

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本文引用的文献

1
Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.第三代免疫菌素：人嘌呤核苷磷酸化酶的无环免疫菌素抑制剂的合成及生物活性
J Med Chem. 2009 Feb 26;52(4):1126-43. doi: 10.1021/jm801421q.
2
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
3
Synthesis and structure-antibacterial activity relationship investigation of isomeric 2,3,5-substituted perhydropyrrolo[3,4-d]isoxazole-4,6-diones.
异构2,3,5-取代全氢吡咯并[3,4-d]异恶唑-4,6-二酮的合成及其结构-抗菌活性关系研究
Bioorg Med Chem. 2007 Mar 15;15(6):2322-33. doi: 10.1016/j.bmc.2007.01.029. Epub 2007 Jan 19.
4
Synthesis of novel isoxazolidine derivatives and their antifungal and antibacterial properties.新型异恶唑烷衍生物的合成及其抗真菌和抗菌性能。
Arch Pharm (Weinheim). 2003 Jun;336(3):159-64. doi: 10.1002/ardp.200390015.
5
New steroidal antiinflammatory antedrugs: steroidal [16 alpha,17 alpha-d]-3'-carbethoxyisoxazolines.
J Med Chem. 1995 Mar 17;38(6):1048-51. doi: 10.1021/jm00006a026.