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食源性肉毒中毒的诊断困难。

Difficulties in diagnosing food-borne botulism.

作者信息

Forss Nina, Ramstad Raimo, Bäcklund Tom, Lindström Miia, Kolho Elina

机构信息

Departments of Neurology, Helsinki University Central Hospital, Helsinki, Finland.

出版信息

Case Rep Neurol. 2012 May;4(2):113-5. doi: 10.1159/000339736. Epub 2012 Jun 21.

DOI:10.1159/000339736
PMID:22807907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3398098/
Abstract

Botulism is a muscle-paralyzing disease caused by neurotoxins (types A-G) produced by the bacteria Clostridium botulinum. Symptoms of food-borne botulism most commonly appear 12-36 h after eating contaminated food, but the earliest neurological symptoms may in some cases start abruptly. Here, we report the cases of two patients with food-borne botulism who were admitted to the neurological emergency room as candidates for intravenous thrombolysis for acute stroke.

摘要

肉毒中毒是一种由肉毒梭菌产生的神经毒素(A - G型)引起的肌肉麻痹疾病。食源性肉毒中毒的症状通常在食用受污染食物后12 - 36小时出现,但在某些情况下,最早的神经症状可能会突然发作。在此,我们报告两例食源性肉毒中毒患者的病例,他们因疑似急性中风而作为静脉溶栓治疗的候选者被收治入神经科急诊室。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d38d/3398098/dd6224217586/crn-0004-0113-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d38d/3398098/dd6224217586/crn-0004-0113-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d38d/3398098/dd6224217586/crn-0004-0113-g01.jpg

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本文引用的文献

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Two cases of food-borne botulism in Finland caused by conserved olives, October 2011.2011 年 10 月,芬兰两起因食用橄榄导致的食源性肉毒中毒病例。
Euro Surveill. 2011 Dec 8;16(49):20034. doi: 10.2807/ese.16.49.20034-en.
2
How does botulinum toxin work?
Ann Neurol. 2000 Jul;48(1):7-8.