两名成年患者并发脉络膜黑色素瘤和非霍奇金淋巴瘤：病例报告
Concomitant choroidal melanoma and non-hodgkin lymphoma in two adult patients: case report.
作者信息
Vlaskamp Marcel, de Wolff-Rouendaal Didi, Jansen Patty M, Luyten Gre P M
机构信息
Department of Ophthalmology, LUMC, Leiden, The Netherlands.
出版信息
Case Rep Ophthalmol. 2012 May;3(2):209-13. doi: 10.1159/000339654. Epub 2012 Jun 19.
OBJECTIVE
To report two cases of concomitant choroidal melanoma and intraocular non-Hodgkin lymphoma in two patients.
DESIGN
Case report.
PARTICIPANTS
Two patients with yellow creamy infiltrates in fundo.
INTERVENTION
Both patients had a complete ophthalmologic evaluation and histology was obtained after enucleation of the affected eye.
MAIN OUTCOME MEASURES
Histology findings of the enucleated eyes.
RESULTS
One patient showed a choroidal melanoma with a primary non-Hodgkin lymphoma located solely in the affected eye. The other patient showed a systemic non-Hodgkin lymphoma with ocular manifestations concomitant with a choroidal melanoma.
CONCLUSIONS
In the presence of yellow creamy infiltrates one should include a choroidal lymphoma in the differential diagnosis even if there is another clear pathologic condition. Furthermore in those cases systemic disease should be excluded.
目的
报告两名患者同时患有脉络膜黑色素瘤和眼内非霍奇金淋巴瘤的病例。
设计
病例报告。
研究对象
两名眼底有黄色奶油状浸润的患者。
干预措施
两名患者均接受了全面的眼科评估，并在摘除患眼后进行了组织学检查。
主要观察指标
摘除眼球的组织学检查结果。
结果
一名患者表现为脉络膜黑色素瘤，原发性非霍奇金淋巴瘤仅位于患眼。另一名患者表现为系统性非霍奇金淋巴瘤伴眼部表现，同时伴有脉络膜黑色素瘤。
结论
在出现黄色奶油状浸润时，即使存在另一种明确的病理状况，鉴别诊断中也应考虑脉络膜淋巴瘤。此外，在这些病例中应排除全身性疾病。
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