De Francesco F, Picciotto M, D'Aquino A, Pitini V, Mesiti M
Istituto di Clinica Oncologica e di Ricerca sui Tumori, Università degli Studi di Messina.
Minerva Dietol Gastroenterol. 1990 Jul-Sep;36(3):157-9.
A retrospective study was carried out in 110 patients who underwent colon resection for cancer of the colon-rectum. Polypoid formation reappeared in 10 (21.5%) patients in whom synchronous polyps were found around carcinoma during initial staging; during the follow-up polyps were only found in 3% of patients in whom synchronous polyps had not been documented. A similar ratio was found in the incidence of neoplastic recurrences which was greater (14%) in patients with synchronous polyps. This incidence was higher in cases with multiple polyps and/or polyps larger than 2 cm in size, and in relation to their histological type. The authors suggest that a more comprehensive operation, for example subtotal colectomy, should be performed in patients at greater risk to develop a second primary carcinoma, and/or that a particularly careful post-operative follow-up should be carried out in these patients.
对110例行结直肠癌结肠切除术的患者进行了一项回顾性研究。在初始分期时发现癌灶周围有同步息肉的10例（21.5%）患者中息肉样病变再次出现；在随访期间，未记录有同步息肉的患者中仅有3%发现息肉。在肿瘤复发率方面也发现了类似的比例，有同步息肉的患者复发率更高（14%）。在有多发性息肉和/或息肉大小大于2 cm的病例中，以及根据息肉的组织学类型，该复发率更高。作者建议，对于发生第二原发性癌风险较高的患者，应进行更全面的手术，如次全结肠切除术，和/或对这些患者进行特别仔细的术后随访。
