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住院癌症康复后症状和功能的可行性和变化。

Feasibility and changes in symptoms and functioning following inpatient cancer rehabilitation.

机构信息

Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.

出版信息

Acta Oncol. 2012 Nov;51(8):1070-80. doi: 10.3109/0284186X.2012.699684. Epub 2012 Jul 19.

Abstract

AIM

The aim was to assess feasibility of a 3 + 1 week inpatient rehabilitation program for cancer survivors, to explore characteristics of the attending participants and examine changes in work status, symptoms and functioning, level of fatigue, exercise and physical performance following rehabilitation.

METHODS

This was an open intervention study involving cancer survivors having completed primary cancer treatment. The multidisiplinary program consisted of physical training, patient education and group sessions. Participant were assessed at primary stay (T0), at follow-up stay 8-12 weeks later (T1), and six months after T1 (T2). Symptoms and functioning were assessed by the European Organization for Research and Treatment Core Quality-of-Life Questionnaire, physical fatigue by Fatigue Questionnaire, physical exercise by The Nord- Trøndelag Health Study Physical Activity Questionnaire and physical performance by aerobic capacity (VO(2max)), 30 second Sit-to-stand (STS) and Maximum Step Length (MSL). Linear mixed models were used in analyses.

RESULTS

One hundred and thirty-four of 163 included participants (82%) completed both rehabilitation stays and returned questionaires at T2. The majority of completers were females (81%), breast cancer survivors (60%), highly educated and with mean age of 52.8 years (SD of 8.1). Participants had higher level of symptoms and fatigue and lower functioning at admission compared to a Norwegian reference population. However, they reported higher physical exercise level and 47% reported improved work status from T0 to T2. Symptoms and functioning, fatigue, physical exercise and physical performance improved significantly from T0 to T1 and were maintained at T2.

CONCLUSIONS

The rehabilitation program was feasible and symptoms and functioning normalized following rehabilitation. The program mainly recruited well-educated breast cancer survivors, reporting relative high level of physical exercise. More focus should be put on recruiting and selecting those who need comprehensive inpatient rehabilitation and also compare the effects of inpatient with outpatient rehabilitation programs.

摘要

目的

评估癌症幸存者为期 3+1 周的住院康复计划的可行性,探讨参与患者的特点,并考察康复后工作状态、症状和功能、疲劳程度、运动和身体表现的变化。

方法

这是一项开放干预研究,纳入了已完成主要癌症治疗的癌症幸存者。多学科方案包括体能训练、患者教育和小组会议。患者在初次住院时(T0)、8-12 周后(T1)的随访住院时和 T1 后 6 个月(T2)时接受评估。使用欧洲癌症研究与治疗组织核心生活质量问卷评估症状和功能,使用疲劳问卷评估身体疲劳,使用北欧特隆赫姆健康研究体力活动问卷评估身体运动,使用有氧能力(VO(2max))、30 秒坐站测试(STS)和最大步长(MSL)评估身体表现。采用线性混合模型进行分析。

结果

在纳入的 163 名患者中,有 134 名(82%)完成了两次住院治疗并在 T2 时返回了问卷。大多数完成者为女性(81%),乳腺癌幸存者(60%),受教育程度较高,平均年龄为 52.8 岁(标准差为 8.1)。与挪威参考人群相比,入院时患者的症状和疲劳程度较高,功能较低。然而,他们报告的身体运动水平较高,47%的人报告工作状态从 T0 到 T2 有所改善。从 T0 到 T1,症状和功能、疲劳、身体运动和身体表现显著改善,并在 T2 时保持。

结论

该康复计划切实可行,康复后症状和功能恢复正常。该方案主要招募了受教育程度较高的乳腺癌幸存者,报告了相对较高的身体运动水平。应更加关注招募和选择那些需要全面住院康复的患者,并比较住院和门诊康复计划的效果。

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