电 Cochleography 和高通过噪声掩蔽听觉脑干反应诊断梅尼埃病的比较。

A comparison of electrocochleography and high-pass noise masking of auditory brainstem response for diagnosis of Ménière's disease.

机构信息

Professional Hearing Services-The Dizziness and Balance Center, Falls Church, Virginia, USA.

出版信息

Int J Audiol. 2012 Oct;51(10):783-7. doi: 10.3109/14992027.2012.699199. Epub 2012 Jul 19.

DOI:10.3109/14992027.2012.699199

PMID:22809268

Abstract

OBJECTIVE

To study differences between electrocochleography (ECochG) and cochlear hydrops analysis masking procedure (CHAMP) in diagnosis of Ménière's disease.

DESIGN

Retrospective case review from a tertiary referral center.

STUDY SAMPLE

Thirty patients suspected to have Ménière's disease were assessed by ECochG and CHAMP tests.

RESULTS

Positivity of ECochG with SP/AP amplitude ratio >.40 or >.35 was compared with CHAMP V-delay or CHAMP R × D. Positive ECochG results were found in 43% (>.40 SP/AP ratio) and 63% (>.35 SP/AP ratio) of patients, comparing to positive CHAMP V delay in 27% and CHAMP R × D in 30% of patients. A significant difference (p <.01) was found between ECochG and CHAMP in diagnostic sensitivity. Also, a positive inter-aural correlation was found in CHAMP results (p <.003), but not in ECochG (p =.082) results.

CONCLUSIONS

ECochG is a more sensitive test than CHAMP in detecting the presence of endolymphatic hydrops in Ménière's patients. CHAMP covaried interaurally in unilateral Ménière's patients whereas ECochG did not.

摘要

目的

研究电 Cochleography（ECochG）与耳蜗积水分析掩蔽程序（CHAMP）在梅尼埃病诊断中的差异。

设计

来自三级转诊中心的回顾性病例研究。

研究样本

30 例疑似梅尼埃病患者接受了 ECochG 和 CHAMP 测试评估。

结果

将 SP/AP 幅度比>0.40 或>0.35 的 ECochG 阳性与 CHAMP V-延迟或 CHAMP R × D 进行比较。阳性 ECochG 结果在 43%（>0.40 SP/AP 比）和 63%（>0.35 SP/AP 比）的患者中发现，阳性 CHAMP V 延迟在 27%和 CHAMP R × D 在 30%的患者中发现。ECochG 和 CHAMP 在诊断敏感性方面存在显著差异（p<.01）。此外，在 CHAMP 结果中发现了阳性的耳间相关性（p<.003），但在 ECochG 结果中没有（p=.082）。