Trinchuk V V, Vit V V, Putienko A A
Oftalmol Zh. 1990(2):108-10.
A new method of retinal detachment simulation includes subretinal administration of ferromagnetic fluid with subsequent action from without by a permanent magnetic field. Retinal detachment was induced in 24 eyes of experimental animals. Of them, clinical picture of total high fibrous detachment of the retina was simulated in 16 eyes, and high rigid detachment occupying 2-3 quadrants of the eye fundus--in 8 eyes. Histologically, the induced retinal detachment was characterized by development of degenerative-proliferative processes in all eye coats. The proposed model allows to obtain different variants of "fresh" and "old" retinal detachments. It is highly reproducible, creates conditions for studying all aspects of pathogenesis of complicated forms of retinal detachment and for development of methods for its treatment.
一种视网膜脱离模拟的新方法包括视网膜下注射铁磁流体，随后通过永久磁场从外部施加作用。在实验动物的24只眼中诱导出视网膜脱离。其中，16只眼模拟了视网膜完全高度纤维性脱离的临床症状，8只眼模拟了占据眼底2 - 3个象限的高度硬性脱离。组织学上，诱导的视网膜脱离的特征是所有眼层均出现退行性 - 增殖性病变。所提出的模型能够获得“新鲜”和“陈旧”视网膜脱离的不同变体。它具有高度可重复性，为研究复杂形式视网膜脱离发病机制的各个方面以及开发其治疗方法创造了条件。
