Department of Plastic and Reconstructive Surgery, North Bristol NHS Trust, Frenchay Hospital, Bristol BS16 1LE, UK.
J Plast Reconstr Aesthet Surg. 2013 Feb;66(2):274-6. doi: 10.1016/j.bjps.2012.06.022. Epub 2012 Jul 17.
Acral lentiginous melanoma affecting the nail is uncommon but carries a poor prognosis due to difficulties in early diagnosis. The gold standard of treatment for subungual melanoma is biopsy followed by wide local excision in form of amputation of the distal phalanx of the digit, in order to achieve at least 10 mm margin of clearance or by fixed tissue micrographic (Mohs') surgery. Here, we demonstrate a non-amputative approach for the excision of subungual melanoma in situ of the right great toe, involving removal of the nail unit with a layer of underlying bone before reconstruction with full thickness skin graft. This technique allows adequate excision margins to ensure full clearance of the lesion with satisfactory preservation of function.
累及甲的肢端雀斑样黑素瘤并不常见,但由于早期诊断困难,预后较差。甲下黑素瘤的金标准治疗方法是活检,然后广泛局部切除,即通过截断指端的远节指骨进行截肢,以实现至少 10 毫米的清除边缘,或采用固定组织显微镜(Mohs)手术。在这里,我们展示了一种非截肢方法,用于原位切除右大足趾的甲下黑素瘤,涉及在全厚皮片移植重建前,切除甲单位及其下的一层骨。该技术可确保充分切除边缘,以彻底清除病变,同时保持满意的功能。