Zhang Jing, Mao Jian, Li Juan, Chen Dan
Departement of Pediatrics, Shengjing Hospital, China Medical University, Shenyang 110004, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2012 Jul;14(7):489-95.
To study the image characteristics of neonatal purulent meningitis caused by different pathogenic bacteria, using conventional magnetic resonance imaging (MRI).
The clinical data of 58 hospitalized newborns with purulent meningitis receiving MRI examination from January 2005 to February 2012 were retrospectively studied. Pathogens and MRI findings were investigated.
Of the 58 newborns, 44 (76%) showed complications of the neural system on the first MRI. Escherichia coli were found as the most common pathogen in newborns with Gram-negative bacteria-induced purulent meningitis (six cases). Of the six cases, four presented with ventriculitis, one with subdural effusion and one with brain infarction on MRI. Listeria monocytogenes was frequently seen in newborns with Gram-positive bacteria-induced purulent meningitis (three cases). All three cases presented with different degrees of white matter damage on MRI.
Neonatal purulent meningitis caused by different pathogenic bacteria has different image characteristics. This suggests that understanding the patterns of MRI findings is useful in the clinical diagnosis and treatment of neonatal purulent meningitis caused by different pathogens.
采用传统磁共振成像（MRI）研究不同病原菌所致新生儿化脓性脑膜炎的影像特征。
回顾性分析2005年1月至2012年2月期间58例住院接受MRI检查的新生儿化脓性脑膜炎的临床资料。对病原菌和MRI表现进行研究。
58例新生儿中，44例（76%）首次MRI检查显示有神经系统并发症。大肠杆菌是革兰阴性菌所致新生儿化脓性脑膜炎最常见的病原菌（6例）。这6例中，4例MRI表现为脑室炎，1例为硬膜下积液，1例为脑梗死。单核细胞增生李斯特菌常见于革兰阳性菌所致新生儿化脓性脑膜炎（3例）。所有3例MRI均表现为不同程度的白质损伤。
不同病原菌所致新生儿化脓性脑膜炎具有不同的影像特征。这表明了解MRI表现模式有助于不同病原菌所致新生儿化脓性脑膜炎的临床诊断和治疗。
