Popov D, Krasteva R, Ivanova R, Mateva L, Krastev Z
Clinic of Gastroenterology, University Hospital "St. Iv. Rilski", 15 Akad. Ivan Geshov Boulevard, 1431 Sofia, Bulgaria.
Int J Nephrol. 2012;2012:961654. doi: 10.1155/2012/961654. Epub 2012 Jul 3.
Introduction. There are limited studies on simultaneous evaluation of liver and renal blood flow using Doppler methods. We evaluated and compared the changes of liver and renal Doppler US parameters in patients with liver cirrhosis according to the degree of liver disease. Material and Methods. We assessed a large spectrum of liver and renal Doppler US parameters in 67 patients with liver cirrhosis. Results. Significant differences between Child's classes or score, as well as MELD score, were observed in all investigated intrarenal blood flow Doppler US parameters, except renal artery peak systolic velocity, but only in some of the hepatic ones. The deviations of renal Doppler US parameters were also related with the complications of liver cirrhosis, as well as serum urea and creatinine levels. There was relationship between Doppler US parameters of hepatic artery and the corresponding renal artery Doppler US parameters. The changes of Doppler US parameters were age independent. Conclusion. Our results show, renal Doppler US parameters correlate with the severity and complications of liver cirrhosis. Because of dynamic deviations of renal Doppler US parameters with advance of liver cirrhosis, we recommend Doppler US of renal artery as a part of follow up of these patients.
引言。关于使用多普勒方法同时评估肝脏和肾脏血流的研究有限。我们根据肝病程度评估并比较了肝硬化患者肝脏和肾脏多普勒超声参数的变化。材料与方法。我们评估了67例肝硬化患者的一系列肝脏和肾脏多普勒超声参数。结果。在所有研究的肾内血流多普勒超声参数中,除肾动脉收缩期峰值流速外,在Child分级或评分以及终末期肝病模型(MELD)评分之间均观察到显著差异,但仅在部分肝脏参数中存在差异。肾脏多普勒超声参数的偏差也与肝硬化并发症以及血清尿素和肌酐水平相关。肝动脉多普勒超声参数与相应肾动脉多普勒超声参数之间存在关联。多普勒超声参数的变化与年龄无关。结论。我们的结果表明,肾脏多普勒超声参数与肝硬化的严重程度和并发症相关。由于随着肝硬化进展肾脏多普勒超声参数会出现动态偏差,我们建议将肾动脉多普勒超声作为这些患者随访的一部分。