Piscaglia F, Donati G, Serra C, Muratori R, Solmi L, Gaiani S, Gramantieri L, Bolondi L
Division of Internal Medicine, University of Bologna, via Albertoni, Bologna, Italy.
Ultrasound Med Biol. 2001 Jul;27(7):893-9. doi: 10.1016/s0301-5629(01)00390-8.
The accuracy of various Doppler parameters of portal circulation in the diagnosis of relevant portal hypertension (presence of gastroesophageal varices) was prospectively validated. The following parameters were compared in 51 patients with chronic liver disease (40 with cirrhosis and 11 with chronic hepatitis): portal vein flow velocity and congestion index, hepatic and splenic arteries resistance indexes (RI), modified liver vascular index (portal flow velocity/hepatic artery RI) and portal hypertension index, a new index calculated as: [(hepatic artery RI x 0.69) x (splenic artery RI x 0.87)]/portal vein flow velocity. Highest accuracy was achieved by the splenic artery RI and the portal hypertension index (both around 75%) at cut-offs, respectively, of 0.60 and 12 cm/s(-1), which appeared to be, therefore, the most favorable parameters for the clinical practice. Their use may limit the need for endoscopy to search for varices.
对门静脉循环的各种多普勒参数在诊断相关门静脉高压(存在胃食管静脉曲张)中的准确性进行了前瞻性验证。在51例慢性肝病患者(40例肝硬化患者和11例慢性肝炎患者)中比较了以下参数:门静脉血流速度和充血指数、肝动脉和脾动脉阻力指数(RI)、改良肝血管指数(门静脉血流速度/肝动脉RI)以及门静脉高压指数,门静脉高压指数是一个新计算的指数:[(肝动脉RI×0.69)×(脾动脉RI×0.87)]/门静脉血流速度。脾动脉RI和门静脉高压指数在截断值分别为0.60和12 cm/s⁻¹时达到最高准确性(均约为75%),因此,这两个参数似乎是临床实践中最有利的参数。使用它们可能会减少内镜检查寻找静脉曲张的必要性。