Lo Russo Giuseppe, Accarpio Fabio, Spinelli Gian Paolo, Miele Evelina, Borrini Francesco, Cerbone Linda, Stati Valeria, Prinzi Natalie, Strudel Martina, Sibio Simone, Tomao Silverio
Department of Medical-Surgical Science and Biothecnology, Oncology Unit, S,Maria Goretti Hospital, Latina - University of Rome "Sapienza" Corso della Repubblica, 04100, Latina, Italy.
J Med Case Rep. 2012 Jul 19;6:212. doi: 10.1186/1752-1947-6-212.
Dukes A stages of colorectal cancer are rarely reported to metastasize. Subcutaneous or skin metastases from colon cancer are rare events and usually indicate widespread disease.
We present the case of a 72-year-old Caucasian woman with Dukes A colorectal cancer at diagnosis and, three years later, a single secondary subcutaneous involvement with no other metastatic sites. The description of this case is supported by critical analysis of its clinical, radiological and pathological features. Our report illustrates that diagnosis can be difficult and controversial when relapse occurs in early stage patients and at uncommon sites.
The unusual and aggressive course of the reported disease stresses the importance of intensive follow-up in colorectal cancer patients with good prognostic factors.
结直肠癌的杜克A期很少有转移的报道。结肠癌的皮下或皮肤转移是罕见事件，通常提示疾病已广泛播散。
我们报告了一名72岁的白种女性，诊断为杜克A期结直肠癌，三年后出现单一的皮下继发性受累，无其他转移部位。对该病例的临床、影像学和病理特征进行批判性分析，支持了本病例的描述。我们的报告表明，早期患者在不常见部位复发时，诊断可能困难且存在争议。
所报道疾病的不寻常且侵袭性病程强调了对具有良好预后因素的结直肠癌患者进行强化随访的重要性。
