Stephens C B, Arnold G E, Butchko G M, Hardy C L
Laryngoscope. 1979 Oct;89(10 Pt 1):1689-96. doi: 10.1002/lary.5540891018.
Seventeen cases of juvenile laryngeal papillomatosis have been seen and treated with microlaryngoscopy, removal of papillomas, and administering of autogenous vaccine. Holinger's original findings could be confirmed. The operation frequency of 9 patients was significantly reduced, 5 were improved, and 3 unchanged. In no case was an undesirable reaction to the vaccine observed. Electron microscopy showed no virus-like particles in the papilloma but a section of a vulvar wart did show the virus.
已观察到17例青少年喉乳头状瘤病患者,并对其进行了显微喉镜检查、乳头状瘤切除及自体疫苗接种治疗。霍林格的原始发现得到了证实。9例患者的手术频率显著降低,5例有所改善,3例无变化。未观察到疫苗有任何不良反应。电子显微镜检查显示乳头状瘤中没有病毒样颗粒,但一例外阴疣切片中确实发现了病毒。