Service de Pharmacie, Hôpital Robert Debré, AP-HP, 48 Boulevard Sérurier, 75935 Paris Cedex 19, France.
Pediatr Infect Dis J. 2012 Dec;31(12):1309-11. doi: 10.1097/INF.0b013e318269cc6a.
We report 6 pediatric cases of tuberculosis caused by Mycobacterium tuberculosis and treated them with levofloxacin or moxifloxacin in the mother-child unit of a university hospital in France between 2005 and 2011. We assess the clinical efficacy and safety of fluoroquinolones and the benefit-risk ratio for their use as second-line antituberculosis drugs in children and adolescents.
我们报告了 6 例在法国一家大学附属医院母婴病房于 2005 年至 2011 年间由结核分枝杆菌引起的结核病患儿病例，这些患儿均接受了左氧氟沙星或莫西沙星治疗。我们评估了氟喹诺酮类药物的临床疗效和安全性，以及将其作为二线抗结核药物在儿童和青少年中使用的利弊比。
