Koponen H, Reinikainen K J, Jolkkonen J T, Riekkinen P J
Moisio Hospital, Mikkeli, Finland.
Acta Neurol Scand. 1990 Nov;82(5):289-91. doi: 10.1111/j.1600-0404.1990.tb03305.x.
Cerebrospinal fluid somatostatin-like immunoreactivity (CSF SLI) was determined for 9 patients with chronic alcohol ingestion and dementia associated with alcoholism and for 8 age-equivalent controls. The CSF SLI was significantly reduced (32%) in the alcoholics with dementia as compared to the controls. This finding is in accordance with previous observations on the relationship between reduced CSF SLI and cognitive impairment in various neuropsychiatric disorders, and extends this finding to patients with dementia associated with alcoholism.
对9例慢性酒精摄入且患有酒精性痴呆的患者以及8例年龄相仿的对照者测定了脑脊液生长抑素样免疫反应性（CSF SLI）。与对照组相比，患有痴呆的酗酒者的CSF SLI显著降低（32%）。这一发现与先前关于CSF SLI降低与各种神经精神疾病认知障碍之间关系的观察结果一致，并将这一发现扩展至患有酒精性痴呆的患者。
