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[慢性非特异性肺部疾病中肺微循环血管的变化]

[Changes in the lesser circulation vessels in chronic nonspecific lung diseases].

作者信息

Kop'eva T N, Orazalieva A M, Biriukov Iu V, Mikhaĭlova L P, Gudovskiĭ L M

出版信息

Arkh Patol. 1990;52(8):28-33.

PMID:2281983
Abstract

Clinicomorphological study of the pulmonary circulation vessels was performed in 20 patients with bronchiectatic disease without right ventricle hypertrophy and in 14 patients with chronic bronchitis complicated with pulmonary heart. Pathology data of persons dying from diseases other than vitium cordis and lung diseases were used as control. Morphological signs of pulmonary hypertension are found in all cases of chronic nonspecific lung diseases. The most pronounced changes develop in the vascular segment starting from arterioles and up to the arteries of muscle type with the diameter of 400 microns. The dependence of the pulmonary arteries changes on the type of lung disease is established. Pathological changes in the walls of the pulmonary circulation vessels, in parallel with pronounced compensatory alterations, are found in cases complicated with pulmonary heart.

摘要

对20例无右心室肥厚的支气管扩张病患者和14例合并肺心病的慢性支气管炎患者的肺循环血管进行了临床形态学研究。以死于非心脏和肺部疾病的人的病理数据作为对照。在所有慢性非特异性肺部疾病病例中均发现了肺动脉高压的形态学征象。最明显的变化发生在从小动脉到直径为400微米的肌型动脉的血管段。确定了肺动脉变化与肺部疾病类型的相关性。在合并肺心病的病例中,发现肺循环血管壁的病理变化与明显的代偿性改变同时存在。

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