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[肺部慢性炎症性疾病中支气管血管的形态变化及其在肺动脉高压发生中的作用]

[Morphology of changes in bronchial vessels in chronic inflammatory diseases of the lungs and their role in the development of pulmonary hypertension].

作者信息

Kop'eva T N, Orazalieva A M, Biriukov Iu V, Gudovskiĭ L M

出版信息

Probl Tuberk. 1993(2):55-8.

PMID:7984576
Abstract

Histologic and morphometric examination comprised surgical and autopsy material of 20 patients with bronchiectatic disease and 14 patients with chronic bronchitis, respectively. The control group consisted of 14 autopsy follow-ups of the lungs of subjects who had neither pulmonary diseases nor heart defects. Structural reorganization of the lungs in both diseases was characterized by enlargement of the middle and inner coats of arteries, hyperplasia of their inner elastic membrane and hypertrophy of the middle coat of veins. Changes mainly developed on the level of the subsegmental bronchi and bronchiectases. A direct correlation was seen between the degree of hypertrophy of the walls of bronchial vessels and those of the pulmonary artery. Participation of bronchopulmonary shunting in the development of lung hypertension is discussed.

摘要

组织学和形态计量学检查分别包括20例支气管扩张症患者和14例慢性支气管炎患者的手术及尸检材料。对照组由14例既无肺部疾病也无心脏缺陷的受试者肺部的尸检随访组成。两种疾病中肺的结构重组表现为动脉中膜和内膜增厚、内弹性膜增生以及静脉中膜肥厚。这些变化主要发生在亚段支气管和支气管扩张部位。观察到支气管血管壁与肺动脉壁的肥厚程度之间存在直接相关性。文中讨论了支气管肺分流在肺动脉高压发生中的作用。

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