Chen Jing, Zou Yuping
Department of Ophthalmology, Guangzhou General Hospital of Guangzhou Military Command, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2012 Jun;32(7):1056-8, 1063.
To evaluate the early therapeutic effect of endoscope-assisted goniosynechialysis combined with phacoemulsification and intraocular lens implantation for management of primary angle-closure glaucoma.
Endoscope-assisted goniosynechialysis combined with phacoemulsification and intraocular lens implantation was performed in 31 patients (31 eyes) with primary angle-closure glaucoma, including 17 eyes with acute angle closure glaucoma and 14 eyes with chronic angle closure glaucoma. The patients were regularly followed up to observe the postoperative complications and changes in the intraocular pressure, visual acuity, anterior chamber depth and anterior chamber angle.
Hyphema occurred in 3 eyes after the operation and was absorbed gradually. The intraocular pressure decreased significantly in all the patients after the operation (P<0.05) but showed no significant differences between the acute and chronic cases (P>0.05). The intraocular pressure was over 21 mmHg in only one eye in the chronic group, and could be controlled by ocular hypotensive agents. Visual acuity improved and the anterior chamber depth increased in all the patients, showing no significant differences between the two groups (P>0.05). The anterior chamber angle all opened after the operation in 16 eyes (94.1%) in acute group, a rate significantly higher than that in the chronic group (9 eyes, 64.3%) (P<0.05). Anterior chamber angle was adhesive in 1 eye in the acute group and in 5 eyes in the chronic group. No further extension of goniosynechiae was found in these cases during the follow-up period.
Endoscope-assisted goniosynechialysis has such advantages as optimized visualization, accuracy and safety in the management of primary angle-closure glaucoma.
评估内镜辅助下房角分离术联合白内障超声乳化吸除及人工晶状体植入术治疗原发性闭角型青光眼的早期疗效。
对31例(31眼)原发性闭角型青光眼患者行内镜辅助下房角分离术联合白内障超声乳化吸除及人工晶状体植入术,其中急性闭角型青光眼17眼,慢性闭角型青光眼14眼。定期随访观察术后并发症及眼压、视力、前房深度和房角的变化。
术后3眼出现前房积血,均逐渐吸收。术后所有患者眼压均显著下降(P<0.05),但急性和慢性病例之间差异无统计学意义(P>0.05)。慢性组仅1眼眼压超过21 mmHg,可通过降眼压药物控制。所有患者视力均提高,前房深度均增加,两组间差异无统计学意义(P>0.05)。急性组16眼(94.1%)术后房角均开放,开放率显著高于慢性组(9眼,64.3%)(P<0.05)。急性组1眼、慢性组5眼房角粘连。随访期间这些病例未见房角粘连进一步扩展。
内镜辅助下房角分离术在原发性闭角型青光眼治疗中具有可视化优化、精准及安全等优点。