Lin Yu-Cheng, Lin Wei-Pin, Huang Jeng-Yi, Lee Shen-Yang
Department of Nephrology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taiwan.
Intern Med. 2012;51(14):1841-3. doi: 10.2169/internalmedicine.51.7485. Epub 2012 Jul 15.
Patients undergoing continuous ambulatory peritoneal dialysis (CAPD) are at an increased risk of peritonitis following colonoscopy with or without polypectomy. Guidelines for peritoneal dialysis patients recommend administration of prophylactic antibiotics and drainage of the abdomen before colonoscopy. In this report, we describe a 53-year-old woman on CAPD who underwent colonoscopy with polypectomy and developed peritonitis within 24 hours. She presented with severe abdominal pain, typical rebounding tenderness, and turbid dialysate containing increased white blood cells with a predominance of neutrophils. A culture of the patient's peritoneal fluid grew polymicrobial species including Escherichia coli, Klebsiella pneumoniae, and Enterococcus faecalis. She was treated with intraperitoneal and intravenous administration of combination antibiotics, and she fully recovered within 3 weeks. We suggest that nephrologists and endoscopists should be familiar with the risks and follow the guidelines to prevent such complications in CAPD patients. If peritonitis occurs, medical therapy with antibiotics should be considered before surgical intervention for catheter salvage.
接受持续性非卧床腹膜透析(CAPD)的患者,在进行有或无息肉切除术的结肠镜检查后发生腹膜炎的风险会增加。腹膜透析患者指南建议在结肠镜检查前给予预防性抗生素并进行腹腔引流。在本报告中,我们描述了一名53岁接受CAPD的女性,她接受了结肠镜检查及息肉切除术,并在24小时内发生了腹膜炎。她出现严重腹痛、典型的反跳痛,浑浊的透析液中白细胞增多,以中性粒细胞为主。患者腹膜液培养出多种微生物,包括大肠杆菌、肺炎克雷伯菌和粪肠球菌。她接受了腹腔内和静脉联合使用抗生素治疗,并在3周内完全康复。我们建议肾病学家和内镜医师应熟悉这些风险并遵循指南,以预防CAPD患者出现此类并发症。如果发生腹膜炎,在进行手术干预以挽救导管之前,应考虑使用抗生素进行药物治疗。